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644706 Sigma-Aldrich

Pd EnCat® TPP30

extent of labeling: 0.4 mmol/g Pd loading, Pd 1.0, TPP 0.8

Synonym: Palladium acetate and triphenylphosphine, microencapsulated in polyurea matrix

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Properties

Related Categories Catalysis and Inorganic Chemistry, Chemical Synthesis, Palladium Catalysts, Pd EnCat
contains   0.26-0.35 mmol/g phosphorous
  0.37-0.44 mmol/g palladium
composition   Pd, 1.0
  TPP, 0.8
reaction suitability   core: palladium
  reaction type: Buchwald-Hartwig Cross Coupling Reaction
  reaction type: Heck Reaction
  reaction type: Hiyama Coupling
  reaction type: Negishi Coupling
  reaction type: Sonogashira Coupling
  reaction type: Stille Coupling
  reaction type: Suzuki-Miyaura Coupling
  reagent type: catalyst
extent of labeling   0.4 mmol/g Pd loading
storage temp.   room temp

Description

General description

It is an encapsulated catalyst (EnCat®), wherein palladium acetate and triphenylphosphine (TPP) are microencapsulated within a polyurea matrix, which prevents palladium leaching.

Application

Reaxa Technology

Pd EnCat® TPP30 may be used as a catalyst for the microwave-assisted Sonogashira cross-coupling of:
• Aryl iodides and bromides with terminal alkynes to form the corresponding coupling products under copper-free conditions.
• Bromobenzotriazoles and arylacetylenes in the presence of 1,5-diazabicyclo[5.4.0]undecene-5-ene (DBU) and copper iodide to form 2H-benzo[d][1,2,3]triazole derivatives.

Recyclable, immobilized catalyst system that simplifies removal of Pd in C-C bond forming and reduction processes.

Packaging

1, 10, 100 g in glass bottle

Features and Benefits

The advantages of using Pd EnCat® catalysts are:
• low residual metal levels in crude product
• easy recovery of catalyst
• compatibility of immobilized metal with various ligands to effect C-C bond forming reactions
• safer and easier to handle than Pd/C for hydrogenation
• efficiency and economy gains through recovery and recycling

Other Notes

Matrix content 30%

Legal Information

PdEncat® technology.

EnCat is a registered trademark of Reaxa Ltd.

Safety & Documentation

Safety Information

Symbol 
Signal word 
Warning
Precautionary statements 
Personal Protective Equipment 
RIDADR 
UN 3175 4.1 / PGII
WGK Germany 
WGK 3
Flash Point(F) 
-9.4 - -7.6 °F
Flash Point(C) 
-23 - -22 °C
Protocols & Articles

Articles

Pd EnCat™ Encapsulated Palladium Catalysts

Homogeneous palladium catalysts are widely utilized due to their versatility, reactivity and functional group tolerance. However, using homogeneous catalysts presents some problems including:
Chemfiles Volume 4 Article 7
Keywords: C-C bond formation, Carbonylations, Catalysis, Coupling reactions, Cross couplings, Diffusion, Filtration, Heck Reaction, Hydrogenations, Immobilization, Ligands, Microwave synthesis, Polymerization reactions, Purification, Reductions, Solvents, Stille coupling, Suzuki coupling

Supported/Encapsulated Palladium Catalysts

Palladium has become one of the most commonly used metal for cross-coupling transformations. However, the use of homogeneous palladium presents several drawbacks that can be overcome by attaching the...
William Sommer
Aldrich ChemFiles 2007, 7.10, 23.
Keywords: Carbonylations, Catalysis, Chemfiles, Coupling reactions, Cross couplings, Immobilization, Ligands

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Easier, Faster, and Cleaner Reactions In partnership with Reaxa Ltd., Sigma-Aldrich is pleased to offer several technology platforms that allow for easier, faster, and cleaner processes. The technolo...
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Peer-Reviewed Papers
15

References

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