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653683 Sigma-Aldrich

5-Nitro-2-oxindole

97%

Synonym: 5-Nitro-1,3-dihydroindole-2-one, NSC 25199, NSC 99066

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Properties

Related Categories Building Blocks, C7 to C9, Chemical Synthesis, Heterocyclic Building Blocks, Indoles More...
InChI Key   JQCGHRDKVZPCRO-UHFFFAOYSA-N
assay   97%
mp   233-236 °C

Description

Packaging

1, 5 g in glass bottle

Application

• Reactant for synthesis of 3-[4-(amino/methylsulfonyl)phenyl]methylene-indolin-2-one derivatives as novel COX-1/2 and 5-LOX inhibitors
• Reactant for preparation of Aurora kinase inhibitors
• Reactant for synthesis of 3-substituted 2-indolinone RET inhibitors
• Reactant for synthesis of 4-azachromeno[2,3-b]indol-11(6H)-ones and derivatives as analogs of ellipticine
• Reactant for preparation of [18F]fluorobenzylidene-indolinone as possible tyrosine kinase inhibitor for PET tumor imaging
• Reactant for preparation of 3-substituted indolin-2-ones as neuroprotective and toxic agents

Safety & Documentation

Safety Information

Symbol 
GHS07  GHS07
Signal word 
Warning
Hazard statements 
Precautionary statements 
Personal Protective Equipment 
RIDADR 
NONH for all modes of transport
WGK Germany 
3

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Protocols & Articles
Peer-Reviewed Papers
15

References

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