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656356 Sigma-Aldrich

(R)-(–)-3-Piperidinecarboxylic acid

97%

Synonym: (R)-(–)-Nipecotic acid

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Properties

Related Categories Asymmetric Synthesis, Chemical Biology, Chemical Synthesis, Chiral Building Blocks, Heterocyclic Building Blocks,
assay   97%
optical activity   [α]22/D −5°, c = 1 in H2O
application(s)   peptide synthesis: suitable
mp   251-255 °C
SMILES string   OC(=O)[C@@H]1CCCNC1
InChI   1S/C6H11NO2/c8-6(9)5-2-1-3-7-4-5/h5,7H,1-4H2,(H,8,9)/t5-/m1/s1
InChI key   XJLSEXAGTJCILF-RXMQYKEDSA-N
Gene Information   human ... SLC6A1(6529), SLC6A11(6538), SLC6A12(6539)
mouse ... Slc6a1(232333)
rat ... Slc6a1(79212), Slc6a12(50676)

Description

General description

(R)-(-)-3-Piperidinecarboxylic acid is an inhibitor of GABA (γ-aminobutyric acid) uptake.

Packaging

1, 10 g in glass bottle

Safety & Documentation

Safety Information

Symbol 
GHS07  GHS07
Signal word 
Warning
Hazard statements 
Precautionary statements 
Target organs 
Respiratory system
Personal Protective Equipment 
RIDADR 
NONH for all modes of transport
WGK Germany 
WGK 3
Flash Point(F) 
Not applicable
Flash Point(C) 
Not applicable

Documents

Certificate of Analysis (COA)

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Protocols & Articles

Articles

Piperidines

Piperidines have become increasingly popular building blocks in a vast array of synthetic protocols. 1-Boc-2-(aminomethyl)piperidine has been used in a post-Ugi carbonylation/intramolecular amidation...
Aldrich ChemFiles 2007, 7.8, 7.
Keywords: Amidations, Building blocks, Carbonylations, Chemfiles, Medicinal chemistry, Protocols

Peer-Reviewed Papers
15

References

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