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  • 676632 - 5-(Di-tert-butylphosphino)-1′, 3′, 5′-triphenyl-1′H-[1,4′]bipyrazole

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676632 Sigma-Aldrich

5-(Di-tert-butylphosphino)-1′, 3′, 5′-triphenyl-1′H-[1,4′]bipyrazole

97%

Synonym: BippyPhos

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Properties

Related Categories Catalysis and Inorganic Chemistry, Chemical Synthesis, Cross-Coupling, Non-Proprietary Phosphine Ligands, Phosphine Compounds,
InChI Key   PTXJGGGNGMPMBG-UHFFFAOYSA-N
assay   97%
mp   169-173 °C
reaction suitability   reagent type: ligand
reaction type: Amidations
  reagent type: ligand
reaction type: Buchwald-Hartwig Cross Coupling Reaction
  reagent type: ligand
reaction type: Coupling Reactions

Description

Packaging

1 g in glass bottle

250 mg in glass bottle

Application

Non-proprietary ligand for palladium-catalyzed amination of aryl halides including aryl chlorides. Works best when the palladium source is Pd2(dba)3 (328774).

Safety & Documentation

Safety Information

RIDADR 
NONH for all modes of transport
WGK Germany 
3
Protocols & Articles

Articles

Aldrich ChemFiles 2007, 7.10, 6.| Non-Proprietary Phosphine Ligands

In the pharmaceutical industry, Pd-catalyzed processes have frequently been relied on for carrying out key bond formations. While there are many ligands that efficiently mediate C–C and C–N bond form...
William Sommer
Aldrich ChemFiles 2007, 7.10, 6.
Keywords: Aminations, Catalysis, Coupling reactions, Cross couplings, Eliminations, Ligands, Pharmaceutical

Peer-Reviewed Papers
15

References

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