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683035 Sigma-Aldrich

1-Trifluoroacetyl piperidine

97%

Synonym: 2,2,2-Trifluoro-1-(piperidin-1-yl)ethanone

  • CAS Number 340-07-8

  • Empirical Formula (Hill Notation) C7H10F3NO

  • Molecular Weight 181.16

  •  MDL number MFCD00466213

  •  PubChem Substance ID 24885744

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Properties

Related Categories Building Blocks, C5 to C7, Chemical Synthesis, Heterocyclic Building Blocks, Piperidines More...
InChI Key   BCJUMGSHTLYECD-UHFFFAOYSA-N
assay   97%
refractive index   n20/D 1.4171
density   1.226 g/mL at 25 °C

Description

Application

Reactant for synthesis of:
• Photoreactive probes that differentiate the binding sites of noncompetitive GABA receptor antagonists
• Photoactive a-mannosides and mannosyl peptides
• Inactivators of human cytochrome P450 2B6
• Photoaffinity labeled fusidic acid analogues
• Hydroxyamides as anticonvulsants
• ET-18-OCH3 with antiproliferative properties

Packaging

5, 25 g in glass bottle

Safety & Documentation

Safety Information

Symbol 
Signal word 
Danger
Hazard statements 
Precautionary statements 
RIDADR 
UN2810 - class 6.1 - PG 3 - EHS - Toxic, liquids, organic, n.o.s., HI: all
WGK Germany 
3
Flash Point(F) 
168.8 °F
Flash Point(C) 
76 °C

Documents

Certificate of Analysis

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Protocols & Articles

Articles

Piperidines

Piperidines have become increasingly popular building blocks in a vast array of synthetic protocols. 1-Boc-2-(aminomethyl)piperidine has been used in a post-Ugi carbonylation/intramolecular amidation...
Aldrich ChemFiles 2007, 7.8, 7.
Keywords: Amidations, Building blocks, Carbonylations, Chemfiles, Medicinal chemistry, Protocols

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