• USA Home
  • 689440 - O-(2-Azidoethyl)heptaethylene glycol

EMAIL THIS PAGE TO A FRIEND
689440 Sigma-Aldrich

O-(2-Azidoethyl)heptaethylene glycol

≥95% (oligomer purity)

Synonym: Azido-PEG (n=7)

  • CAS Number 352439-36-2

  • Empirical Formula (Hill Notation) C16H33N3O8

  • Molecular Weight 395.45

  •  Beilstein/REAXYS Number 8940056

  •  MDL number MFCD08274607

  •  PubChem Substance ID 329761266

  •  NACRES NA.22

Purchase

Properties

Related Categories Aliphatic Azides, Azide (-N3) Functionalized, Azide-PEG-Hydroxyl (N3-PEG-OH), Azides, Building Blocks,
Quality Level   100
assay   ≥95% (oligomer purity)
mol wt   average Mn 400
reaction suitability   reaction type: click chemistry
  reagent type: cross-linking reagent
Ω-end   hydroxyl
α-end   azide
storage temp.   2-8°C
SMILES string   OCCOCCOCCOCCOCCOCCOCCOCCN=[N+]=[N-]
InChI   1S/C16H33N3O8/c17-19-18-1-3-21-5-7-23-9-11-25-13-15-27-16-14-26-12-10-24-8-6-22-4-2-20/h20H,1-16H2
InChI key   BUMODEBRFGPXRM-UHFFFAOYSA-N

Description

Application

O-(2-Azidoethyl)heptaethylene glycol is used to synthesize oligo and poly(ethylene glycol) derivatives that are used as structural units of dendrimers, hydrogels, surface modifiers, self-assembling systems and molecular crosslinkers. This precursor is compatible for acetylene-azide click reactions.

Some of the reported applications include:
• Synthesis of strain-stiffening hydrogels through self-assembly of oligomers fibres derived from Azido-PEG (n=7).
• Synthesis of biodegradable tetra-PEG hydrogels for drug delivery system.
• Synthesis of heterobifunctional oligo(ethylene glycol) linkers for bioconjugation and targeted drug delivery.
• Preparation of synthetic amphiphiles for programmed pH-dependent dispersions of carbon nanotubes (CNTs).
• Selective glycoprotein detection through allosteric click-imprinting by using a self-assembled monolayer developed from the above oligomer.
• Preparation of bioactivated quantum dot micelles containing fluorescent nanocrystals.

Packaging

250 mg in glass bottle

Bottomless glass bottle. Contents are inside inserted fused cone.

Safety & Documentation

Safety Information

Symbol 
GHS07  GHS07
Signal word 
Warning
Hazard statements 
Precautionary statements 
Target organs 
Respiratory system
Personal Protective Equipment 
RIDADR 
NONH for all modes of transport
WGK Germany 
WGK 3
Flash Point(F) 
Not applicable
Flash Point(C) 
Not applicable

Documents

Certificate of Analysis (COA)

Please Enter a Lot Number

Meet Synthia - Retrosynthesis Sofware
Protocols & Articles

Articles

Cell Culture Scaffolds via Bio-orthogonal Click Reactions

1,2Malar A. Azagarsamy, 1Navakanth R. Gandavarapu, 1,2Kristi S. Anseth* 1Department of Chemical and Biological Engineering and 2the Howard Hughes Medical Institute, University of Colorado at Boulder,...
Keywords: Addition reactions, Adhesion, Biomaterials, Catalysis, Cell culture, Cell signaling, Chemical reactions, Click chemistry, Cycloadditions, Degradations, Growth factors, Huisgen Cycloaddition, Ligands, Michael Addition, Peptide synthesis, Polymerization reactions, Step-growth polymerization

Degradable Poly(ethylene glycol) Hydrogels for 2D and 3D Cell Culture

Progress in biotechnology fields such as tissue engineering and drug delivery is accompanied by an increasing demand for diverse functional biomaterials. For decades, research in polymeric biomateria...
Keywords: Absorption, Angiogenesis, Biomaterials, Catalysis, Cell culture, Degradations, Eliminations, Growth factors, Infrared spectroscopy, Ligands, Michael Addition, Polymerization reactions, Ring-opening polymerization

Polyethylene Glycol (PEG) Selection Guide

Poly(ethylene glycol) (PEG) is a synthetic, hydrophilic, biocompatible polymer with widespread use in biomedical and other applications. PEGs are synthesized using a ring-opening polymerization of et...
Keywords: Adhesion, Bacterial conjugations, Click chemistry, Molecular biology, PEGylations, Polymerization reactions, Ring-opening polymerization

Peer-Reviewed Papers
15

References

Related Products

Technical Service:

Our team of scientists has experience in all areas of research including Life Science, Material Science, Chemical Synthesis, Chromatography, Analytical and many others.

Bulk Ordering & Pricing:

Need larger quantities for your development, manufacturing or research applications?