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715670 Sigma-Aldrich

2-(Bromoacetyl)benzofuran

97%

Synonym: 1-(Benzo[b]furan-2-yl)-2-bromoethan-1-one, 1-(1-Benzofuran-2-yl)-2-bromoethan-1-one, 1-(1-Benzofuran-2-yl)-2-bromoethanone, 1-(2-Benzofuryl)-2-bromo-1-ethanone, 1-(Benzofuran-2-yl)-2-bromoethanone, 1-Benzo[b]furan-2-yl-2-bromoethanone, 2-(2-Bromoacetyl)benzofuran, 2-(Bromoacetyl)benzo[b]furan, 2-Benzofuranyl bromomethyl ketone, 2-Benzofuryl bromomethyl ketone

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Properties

Related Categories Benzofurans, Building Blocks, Chemical Synthesis, Heterocyclic Building Blocks
InChI Key   NVRNCBWTEDOAQA-UHFFFAOYSA-N
assay   97%
mp   86-90 °C

Description

Packaging

1 g in glass bottle

Application

Reactant for:
• Eschenmoser coupling reaction
• Preparation of β-oxo sulfones as substrates for stereoselective Michael addition/cross-benzoin cascade reactions
• Preparation of thienylpyrazole-based thiazoles and pyrazolines as antimicrobial, antioxidant, anti-inflammatory, and analgesic agents
• Preparation of isatin-(benzofuryl-thiazolyl)-hydrazones by cyclocondensation with isatin-thiosemicarbazones under microwave irradiation as antimicrobial agents
• Synthesis of 2-naphthyl ethers as a protective agent against DNA damage induced by bleomycin-iron
• Asymmetric synthesis of β-dialkylamino alcohols by Ru-catalyzed transfer hydrogenation of α-dialkylamino ketones

Safety & Documentation

Safety Information

Symbol 
Signal word 
Danger
Hazard statements 
Precautionary statements 
RIDADR 
UN 3261 8 / PGII
WGK Germany 
2

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Protocols & Articles
Peer-Reviewed Papers
15

References

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