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724459 Sigma-Aldrich

Poly(N-isopropylacrylamide), carboxylic acid terminated

average Mn 10,000

Synonym: NIPAM polymer, PNIPAM-COOH, Polyacrylamide, functionalized polyNIPAM, functionalized polyacrylamide, polyNIPAM

  • Linear Formula (C6H11NO)nSCH2CH2CO2H

  •  NACRES NA.23

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Properties

Related Categories Hydrophilic Polymers, Materials Science, PNIPAM, Poly(N-isopropylacrylamide) (PNIPAM), Poly(N-isopropylacrylamide) (PNIPAM) and Polyacrylamide (PAM),
Quality Level   100
form   powder
mol wt   average Mn 10,000 by GPC (THF w/ 5%TEA, PS, RI)
  average Mn 10,000
mp   >300 °C

Description

Application

PNIPAM-based Smart Surfaces for Cell Sheet Tissue Engineering

Novel polymer for development of thermosensitive coated micro/nano materials including thermoresponsive polymeric drug delivery systems. The carboxylic acid functional group can be used to conjugate a variety of biomolecules to the polymer chain.

Packaging

5 g in glass bottle

Safety & Documentation

Safety Information

RIDADR 
NONH for all modes of transport
WGK Germany 
WGK 1
Flash Point(F) 
Not applicable
Flash Point(C) 
Not applicable

Documents

Certificate of Analysis (COA)

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Protocols & Articles

Articles

Functional Polymers for Biomedical Applications

Wide range of functional polymers for biomedical applications have been synthesized and structurally characterized. Several classes of polymers including biodegradable polymers, hydrophilic & amphiph...
Gangadhar Panambur, Donghun Koo, Philip Dimitrov, Shahinur Rehman, Bryce Nelson, Viktor Balema
SoftMaterials@sial.com
Keywords: Biomaterials, Building blocks, Polymerization reactions, Reversible addition-fragmentation chain transfer polymerizations

Micro- and Nanofabricated Biomaterials for the Study of Cells and Microtissues

Phin Peng Lee, Karen E. Samy, Miquella G. Chavez, Alec Cerchiari, Tejal A. Desai* Department of Bioengineering and Therapeutic Sciences, University of California San Francisco, San Francisco, CA 9415...
Keywords: Absorption, Adhesion, Amplification, Apoptosis, Biomaterials, Cancer, Cell culture, Cell proliferation, Diffusion, Immobilization, Indicators, Infrared spectroscopy, Ligands, Magnetic resonance imaging, Materials Science, Microscopy, Molecular biology, Nanotechnology, Semiconductor, Solvents

Poly(N-isopropylacrylamide)-based Smart Surfaces for Cell Sheet Tissue Engineering

Tissue engineering has become a key therapeutic tool in the treatment of damaged or diseased organs and tissues, such as blood vessels and urinary bladders.1 Nonetheless, major challenges still need ...
Masamichi NakayamaTeruo Okano and Françoise M. Winnik
Material Matters 2010, 5.3, 56.
Keywords: Adhesion, Biomaterials, Cell culture, Clinical, Dehydration reaction, Growth factors, Hydration reaction, Immobilization, Inflammation, Ligands, Magnetic resonance spectroscopy, Polymerization reactions, Radical polymerization, Rearrangements, Reversible addition-fragmentation chain transfer polymerizations, Solvents

Stimuli-Responsive Materials as Intelligent Drug Delivery Systems

Amit Singh and Mansoor M. Amiji* Department of Pharmaceutical Sciences, School of Pharmacy Northeastern University, Boston, MA 02115 USA *Email: m.amiji@neu.edu; Tel: 617-373-3137
Keywords: Absorption, Aerobic, Angiogenesis, Apoptosis, Atomic absorption spectroscopy, Cancer, Chromatin immunoprecipitation, Clinical, Deprotonations, Diseases, Electron spin resonance, Enzyme activity, Gastrointestinal, Glycolysis, Growth factors, Infrared spectroscopy, Ligands, Magnetic resonance imaging, Materials Science, Nanomaterials, Nanotubes, Pharmaceutical, Polymerization reactions, Sol-gel, transformation

Related Content

NIPAM based Polymers

Stimuli-responsive polymers, also known as “smart” polymers or “environmentally sensitive” polymers, undergo rapid changes in their microstructure from a hydrophilic to a hydrophobic state, triggered...
Keywords: Adsorption, Bacterial conjugations, Biological processes, Separation

Peer-Reviewed Papers
15

References

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