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745774 Sigma-Aldrich

8-Amino-1-octanethiol hydrochloride

95%

Synonym: 8-Mercaptooctylamine hydrochloride

  • CAS Number 937706-44-0

  • Empirical Formula (Hill Notation) C8H19NS · HCl

  • Molecular Weight 197.77

  •  MDL number MFCD28016329

  •  PubChem Substance ID 329765011

  •  NACRES NA.23

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Properties

Related Categories Functional Thiols, Materials Science, Micro/NanoElectronics, Self Assembly and Lithography, Self-Assembly Materials,
Quality Level   100
assay   95%
mp   158-163 °C
storage temp.   2-8°C
SMILES string   SCCCCCCCCN.Cl
InChI   1S/C8H19NS.ClH/c9-7-5-3-1-2-4-6-8-10;/h10H,1-9H2;1H
InChI key   CCWZBRKMJBSNQS-UHFFFAOYSA-N

Description

General description

8-Amino-1-octanethiol hydrochloride (8-AOT) is an amine based alkanethiol that can be used as a self-assembled monolayer (SAM) on a variety of surfaces. It facilitates the immobilization of surface atoms and controls the physiochemical properties of the substrate.

Application

8-AOT can be used in the surface functionalization of gold electrodes for the trace analysis of oligonucleotide using poly nucleic acid (PNA) based ion-channel sensors. It can be used in the fabrication of peptide microarray for surface plasmon resonance based screening of protein kinase activity.

Self Assembly Molecules (SAMs); the amino group is usually modified using amine-reactive materials; such as proteins or biomaterials; to functionalize the gold surface. It is used for biosenors with large amounts of immobilized protein and suppression of nonspecific adsorption

Packaging

250 mg in glass insert

Safety & Documentation

Safety Information

Symbol 
GHS09  GHS09
Signal word 
Warning
Hazard statements 
Precautionary statements 
RIDADR 
UN 3077 9 / PGIII
WGK Germany 
WGK 3
Flash Point(F) 
Not applicable
Flash Point(C) 
Not applicable

Documents

Certificate of Analysis (COA)

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Protocols & Articles
Peer-Reviewed Papers
15

References

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