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746193 Sigma-Aldrich

Maleimide-PEG6-succinimidyl ester

Synonym: 25-(2,5-Dihydro-2,5-dioxo-1H-pyrrol-1-yl)-23-oxo-4,7,10,13,16,19-hexaoxa-22-azapentacosanoic acid 2,5-dioxo-1-pyrrolidinyl ester, Maleimide-PEG6-NHS ester

  • CAS Number 1137109-21-7

  • Empirical Formula (Hill Notation) C26H39N3O13

  • Molecular Weight 601.60

  •  MDL number MFCD11041093

  •  PubChem Substance ID 329765747

  •  NACRES NA.22

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Properties

Related Categories Amine to Sulfhydryl, Chemical Biology, Chemical Synthesis, Crosslinkers, Linkers and Crosslinkers More...
reaction suitability   reagent type: cross-linking reagent
storage temp.   −20°C
SMILES string   O=C1CCC(N1OC(CCOCCOCCOCCOCCOCCOCCNC(CCN2C(C=CC2=O)=O)=O)=O)=O
InChI   1S/C26H39N3O13/c30-21(5-8-28-22(31)1-2-23(28)32)27-7-10-37-12-14-39-16-18-41-20-19-40-17-15-38-13-11-36-9-6-26(35)42-29-24(33)3-4-25(29)34/h1-2H,3-20H2,(H,27,30)
InChI key   AVCPTIUOZBWCKE-UHFFFAOYSA-N

Description

Application

Heterobifunctional crosslinker with an ethylene oxide spacer for linking amine- to sulfhydryl-containing compounds or biomolecules. Maleimide functional group will react with sulfhydryls and the succinimidyl ester group will react with amines. Spacer length is 31.7 angstroms.

Packaging

50, 250 mg in amber glass bottle

Safety & Documentation

Safety Information

RIDADR 
NONH for all modes of transport
WGK Germany 
WGK 3
Flash Point(F) 
Not applicable
Flash Point(C) 
Not applicable

Documents

Certificate of Analysis (COA)

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Certificate of Origin (COO)

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Protocols & Articles

Articles

Polyethylene Glycol (PEG) Selection Guide

Poly(ethylene glycol) (PEG) is a synthetic, hydrophilic, biocompatible polymer with widespread use in biomedical and other applications. PEGs are synthesized using a ring-opening polymerization of et...
Keywords: Adhesion, Bacterial conjugations, Click chemistry, Molecular biology, PEGylations, Polymerization reactions, Ring-opening polymerization

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