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  • 757837 - Poly(ethylene glycol) 2-mercaptoethyl ether acetic acid

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757837 Sigma-Aldrich

Poly(ethylene glycol) 2-mercaptoethyl ether acetic acid

average Mn 3,500

Synonym: mercaptoPEG acid, mercaptopoly(ethylene glycol) carboxylic acid, mercaptopolyoxyethylene acetic acid, thio-PEG, thiol-PEG-carboxylate, thiol-PEG-acid

  • CAS Number 165729-81-7

  • Linear Formula HSC2H4O(C2H4O)nCH2CO2H

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Properties

Related Categories COOH Functionalized, COOH-PEG-Thiol (COOH-PEG-SH), Heterobifunctional PEGs, Materials Science, Poly(ethylene glycol) and Poly(ethylene oxide),
Quality Level   100
form   solid
mol wt   PEG average Mn 3,400 (n~77)
  average Mn 3,500
transition temp   Tm 52-57 °C
Ω-end   thiol
α-end   carboxylic acid
polymer architecture   shape : linear
functionality : heterobifunctional
reaction suitability   reagent type: cross-linking reagent
reactivity: amine reactive
  reagent type: cross-linking reagent
reactivity: thiol reactive
storage temp.   −20°C

Description

Packaging

500 mg in glass insert

Application

Reported applications include: bioconjugation, drug delivery, PEG hydrogel, crosslinker, and surface functionalization.

Safety & Documentation

Safety Information

RIDADR 
NONH for all modes of transport
WGK Germany 
WGK 3
Flash Point(F) 
604.4 °F
Flash Point(C) 
> 318 °C

Documents

Certificate of Analysis (COA)

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Protocols & Articles

Articles

Cell Culture Scaffolds via Bio-orthogonal Click Reactions

1,2Malar A. Azagarsamy, 1Navakanth R. Gandavarapu, 1,2Kristi S. Anseth* 1Department of Chemical and Biological Engineering and 2the Howard Hughes Medical Institute, University of Colorado at Boulder,...
Keywords: Addition reactions, Adhesion, Biomaterials, Catalysis, Cell culture, Cell signaling, Chemical reactions, Click chemistry, Cycloadditions, Degradations, Growth factors, Huisgen Cycloaddition, Ligands, Michael Addition, Peptide synthesis, Polymerization reactions, Step-growth polymerization

Polyethylene Glycol (PEG) Selection Guide

Poly(ethylene glycol) (PEG) is a synthetic, hydrophilic, biocompatible polymer with widespread use in biomedical and other applications. PEGs are synthesized using a ring-opening polymerization of et...
Keywords: Adhesion, Bacterial conjugations, Click chemistry, Molecular biology, PEGylations, Polymerization reactions, Ring-opening polymerization

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