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772828 Sigma-Aldrich

5-Norbornene-2-endo-acetic acid

Synonym: Bicyclo[2.2.1]hept-5-en-2-ylacetic acid, Norbornene acetic acid

  • CAS Number 825-71-8

  • Empirical Formula (Hill Notation) C9H12O2

  • Molecular Weight 152.19

  •  PubChem Substance ID 329766608

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Properties

Related Categories Alicyclic/Etch-Resistant Monomers, Alkenes, Building Blocks, Chemical Biology, Chemical Synthesis,
Quality Level   100
refractive index   n20/D 1.495
density   1.124 g/mL at 25 °C
InChI   1S/C9H12O2/c10-9(11)5-8-4-6-1-2-7(8)3-6/h1-2,6-8H,3-5H2,(H,10,11)/t6-,7+,8?/m1/s1
InChI key   HRVGJQMCNYJEHM-KVARREAHSA-N

Description

Application

Carboxylic acid functionalized norbornene. Carboxylic acid can be used to modify amine containing compounds such as lysine residues on proteins/peptides via standard peptide coupling methods. Norbornene has been shown to react with 1,2,4,5-tetrazines in an inverse electron demand Diels-Alder cycloaddition reaction, which is a bioorthogonal click chemistry reaction demonstrated to be useful in biological imaging applications.

Packaging

1 g in glass bottle

250 mg in amber glass bottle

Safety & Documentation

Safety Information

Symbol 
GHS07  GHS07
Signal word 
Warning
Hazard statements 
Precautionary statements 
RIDADR 
NONH for all modes of transport
WGK Germany 
WGK 3
Flash Point(F) 
Not applicable
Flash Point(C) 
Not applicable

Documents

Certificate of Analysis (COA)

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Meet Synthia - Retrosynthesis Sofware
Protocols & Articles
Peer-Reviewed Papers
15

References

Related Products

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Product #

Description

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903647 1-Heptyl-2-norbornene, ≥95%

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