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774405 Aldrich

(S)-2-Aminobutane-1,4-dithiol hydrochloride

99% (titration)

Synonym: (2S)-2-Amino-1,4-dimercaptobutane hydrochloride, (S)-2-Aminobutane-1,4-dithiol hydrochloride, DTBA, Dithiobutylamine

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Properties

Related Categories Chemical Synthesis, Molecular Biology, Other Synthetic Reagents for Reduction, Protein Modification, Protein Structural Analysis,
InChI Key   HWWPXJZINVJNBM-WCCKRBBISA-N
assay   99% (titration)
mp   210-225 °C
storage temp.   2-8°C

Description

Packaging

1 g in glass bottle

25 g in poly bottle

Application

Dithiobutylamine or DTBA is a new biological reducing reagent with enhanced properties over other commonly used reagents. DTBA was shown to reduce small molecule disulfides 3-5x faster than DTT and was able to reduce (activate) the cysteine dependent protease papain 14x faster than DTT. In addition, due to the presence of the primary amine group, removal of DTBA from mixtures after use is simplified and can be achieved using cation exchange resin.

Safety & Documentation

Safety Information

Symbol 
GHS07  GHS07
Signal word 
Warning
Hazard statements 
Precautionary statements 
RIDADR 
NONH for all modes of transport
WGK Germany 
3
Protocols & Articles

Articles

Raines Group – Products available at Aldrich from the Raines Laboratory

From our library of Articles, Sigma-Aldrich presents Raines Group – Products available at Aldrich from the Raines Laboratory
Keywords: Cancer, Chemical biology, Clinical, Enzymology, Peptide synthesis

UHPLC Analyses of Reduced Infliximab on BIOshell™ IgG 1000 Ã… C4 and BIOshell A400 Protein C4

From our library of Articles, Sigma-Aldrich presents UHPLC Analyses of Reduced Infliximab on BIOshell™ IgG 1000 Ã… C4 and BIOshell A400 Protein C4
Keywords: High performance liquid chromatography, Pharmaceutical, Reductions

UHPLC Analysis of Reduced Humira on BIOshell IgG 1000 Å C4

From our library of Articles, Sigma-Aldrich presents UHPLC Analysis of Reduced Humira on BIOshell IgG 1000 Å C4
Keywords: High performance liquid chromatography, Reductions

UHPLC Analysis of Reduced IgG4 on BIOshell IgG 1000 Å C4

From our library of Articles, Sigma-Aldrich presents UHPLC Analysis of Reduced IgG4 on BIOshell IgG 1000 Å C4
Keywords: Diseases, Gene expression

Peer-Reviewed Papers
15

References

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