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777129 Sigma-Aldrich

N,N-Diethylmethacrylamide

contains <500 ppm MEHQ as inhibitor, 97%

Synonym: DEMAAM, DEMAM

  • CAS Number 5441-99-6

  • Empirical Formula (Hill Notation) C8H15NO

  • Molecular Weight 141.21

  •  MDL number MFCD00078297

  •  PubChem Substance ID 329767886

  •  NACRES NA.23

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Properties

Related Categories Acrylamide and Methacrylamide, Acrylic Monomers, Materials Science, Monomers, Polymer Science More...
Quality Level   100
assay   97%
form   liquid
contains   <500 ppm MEHQ as inhibitor
refractive index   n20/D 1.455
density   0.901 g/mL at 25 °C
storage temp.   2-8°C
SMILES string   CCN(CC)C(=O)C(C)=C
InChI   1S/C8H15NO/c1-5-9(6-2)8(10)7(3)4/h3,5-6H2,1-2,4H3
InChI key   JMCVCHBBHPFWBF-UHFFFAOYSA-N

Description

General description

Post polymerization, N, N-Diethyl methacrylamide gels show temperature sensitivity because of their lower critical solution temperature (LCST). This acrylamide is commonly polymerized to form temperature sensitive hydrogels. The presence of a hydrophobic group (methyl and ethyl group in this case) is characteristic in temperature sensitive polymers. Water solubility in such polymers decreases with increase in temperature.

Application

Since the lower critical solution temperature (LCST) is around body temperature, it is widely used in the development of drug delivery systems based on the sol gel phase conversion at body temperature.

Packaging

5 g in glass bottle

Safety & Documentation

Safety Information

RIDADR 
UN 1993 / PGIII
WGK Germany 
WGK 3
Flash Point(F) 
183.0 °F
Flash Point(C) 
83.88 °C

Documents

Certificate of Analysis (COA)

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Protocols & Articles
Peer-Reviewed Papers
15

References

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