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779431 Sigma-Aldrich

γ-Cyclodextrin

produced by Wacker Chemie AG, Burghausen, Germany, ≥90.0% cyclodextrin basis (HPLC)

Synonym: Cavamax® W8, Cyclomaltooctaose, Cyclooctaamylose, Schardinger γ-Dextrin, gamma-Cyclodextrin

  • CAS Number 17465-86-0

  • Empirical Formula (Hill Notation) C48H80O40

  • Molecular Weight 1297.12

  •  Beilstein/REAXYS Number 78740

  •  EC Number 241-482-4

  •  MDL number MFCD00009595

  •  PubChem Substance ID 329768038

  •  NACRES NA.22

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Properties

Related Categories Alcohols, Building Blocks, C11 to C30+, C22 to C40+, Chemical Synthesis,
grade   produced by Wacker Chemie AG, Burghausen, Germany
InChI Key   GDSRMADSINPKSL-HSEONFRVSA-N
assay   ≥90.0% cyclodextrin basis (HPLC)
loss   ≤11.0% loss on drying

Description

General description

Gamma-cyclodextrin (γ-CD) is a cyclic α-1,4-glucan linked oligosaccharide that is widely used in the food and pharmaceutical industries because of its high water solubility, larger internal cavity, and bioavailability.

Application

γ-Cyclodextrin can be used as a precursor for the synthesis of:
• Octakis-(2,3-di-O-methyl-6-O-carboxymethyl)-γ-cyclodextrin sodium salt (ODMCM). ODMCM is used in capillary electrophoresis as a chiral resolving agent.
• Water-soluble cyclodextrin thioethers derivatives for the transportation of hydrophobic drugs.

Legal Information

Cavamax is a registered trademark of Wacker Chemie AG

Cavasol is a registered trademark of Wacker Chemie AG

Safety & Documentation

Safety Information

RIDADR 
NONH for all modes of transport
WGK Germany 
2

Documents

Certificate of Analysis (COA)

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Setting the Standard for Solid Formulation
Protocols & Articles
Peer-Reviewed Papers
15

References

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