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  • 78133 - O-(6-Chlorobenzotriazol-1-yl)-N,N,N′,N′-tetramethyluronium tetrafluoroborate

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78133 Sigma-Aldrich

O-(6-Chlorobenzotriazol-1-yl)-N,N,N′,N′-tetramethyluronium tetrafluoroborate

98%

Synonym: 1-[Bis(dimethylamino)methylen]-5-chlorobenzotriazolium 3-oxide tetrafluoroborate, N,N,N′,N′-Tetramethyl-O-(6-chloro-1H-benzotriazol-1-yl)uronium tetrafluoroborate, TCTU

  • CAS Number 330641-16-2

  • Empirical Formula (Hill Notation) C11H15BClF4N5O

  • Molecular Weight 355.53

  •  MDL number MFCD04973270

  •  PubChem Substance ID 57652724

  •  NACRES NA.22

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Properties

Related Categories Chemical Biology, Chemical Synthesis, Coupling, Peptide Coupling, Peptide Synthesis and Peptide Chemistry,
Quality Level   100
assay   ≥97.5% (HPLC)
  98%
application(s)   peptide synthesis: suitable
impurities   ≤0.5% water
SMILES string   F[B-](F)(F)F.CN(C)C(\On1nnc2ccc(Cl)cc12)=[N+](/C)C
InChI   1S/C11H15ClN5O.BF4/c1-15(2)11(16(3)4)18-17-10-7-8(12)5-6-9(10)13-14-17;2-1(3,4)5/h5-7H,1-4H3;/q+1;-1
InChI key   GBGVQFJZGHBZMC-UHFFFAOYSA-N

Description

Application

Coupling reagent for:
• Synthesis via plate-based multiple parallel centrifugation synthesizer
• Solid-phase synthesis of cyclic gramicidin analogs
• Comparison of automatic multiple peptide synthesizers
• Solid-phase peptide coupling with lack of racemization

Packaging

5, 25, 100 g in poly bottle

Safety & Documentation

Safety Information

Symbol 
Signal word 
Danger
Hazard statements 
Precautionary statements 
Personal Protective Equipment 
RIDADR 
NONH for all modes of transport
WGK Germany 
WGK 3
Flash Point(F) 
Not applicable
Flash Point(C) 
Not applicable
Protocols & Articles

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Peer-Reviewed Papers
15

References

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