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79380 Sigma-Aldrich

Phosgene solution

~20% in toluene

  • CAS Number 75-44-5

  • Linear Formula COCl2

  • Molecular Weight 98.92

  •  Beilstein/REAXYS Number 1098367

  •  MDL number MFCD00036119

  •  PubChem Substance ID 57652789

  •  NACRES NA.22

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Properties

Related Categories Chemical Synthesis, Coupling, Phosgene Derivatives, Synthetic Reagents
Quality Level   200
concentration   ~20% in toluene
impurities   ≤300 mg/kg benzene
storage temp.   2-8°C
SMILES string   ClC(Cl)=O
InChI   1S/CCl2O/c2-1(3)4
InChI key   YGYAWVDWMABLBF-UHFFFAOYSA-N
Safety & Documentation

Safety Information

Signal word 
Danger
Target organs 
Central nervous system, Lungs
RIDADR 
UN3489 - class 6.1 - PG 1 - acidic - RQ - Toxic by inhalation liquid, flammable, corrosive, n.o.s., HI: all (not BR)
WGK Germany 
WGK 3
Protocols & Articles

Articles

Phosgene

Phosgene is an extremely versatile reagent allowing easy access to isocyanates, ureas, carbamates, carbonates, acyl and alkyl chlorides.1 Many of these can be used as reactive intermediates in peptid...
Matthias Junkers
ChemFiles 2007, 7.2, 4.
Keywords: Coupling reactions, Peptide synthesis

Peer-Reviewed Papers
15

References

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