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  • 797316 - 1-{4-[1,2-Diphenyl-2-(p-tolyl)vinyl]phenyl}-1H-pyrrole-2,5-dione

797316 Sigma-Aldrich


Synonym: TPE-Thiol

  • CAS Number 1245606-71-6

  • Empirical Formula (Hill Notation) C31H23NO2

  • Molecular Weight 441.52

  •  PubChem Substance ID 329768584



General description

Aggregation-induced emission luminogens (AIEgen) were tailored to detect biological thiols. Maleimide is attached to the TPE core, giving TPE-Thiol.16. The reaction is inspired by the fast and efficient thiolene click reaction between maleimide and thiols, TPE-Thiol is not emissive in both solution and aggregated states, due to the photo-induced electron transfer from TPE to maleimide. However, reaction with thiol groups can interrupt the electron transfer process and turn-on the emission of TPE. TPE-Thiol can be used for labelling of protein carrying cysteine residues in the physiological media and poly(acrylamide) gel electrophoresis assays.


TPE-Thiol is an aggregation-induced emission (AIE) material for the "Click" chemistry, with alkene and thio group detection.


25 mg in glass insert

Safety & Documentation

Safety Information

NONH for all modes of transport


Certificate of Analysis (COA)

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Protocols & Articles


AIE Luminogens: A Family of New Materials with Multifaceted Functionalities

a HKUST Shenzhen Research Institute, No. 9 Yuexing 1st RD, South Area, Hi-tech Park, Nanshan, Shenzhen 518057, China
Engui Zhaoa,b and Ben Zhong Tang*,a,b,c

Keywords: Apoptosis, Biological processes, Cancer, Capillary electrophoresis, Crystallization, Diagnostic, Diseases, Electronics, Electrophoresis, Eliminations, Esterifications, Evaporation, Gel electrophoresis, Gene expression, High performance liquid chromatography, Microscopy, Neuroscience, Nucleic acid denaturation, Optical microscopy, Protein assay, Separation, Solvation, Thin layer chromatography, Williamson ether synthesis

Aggregation-induced Emission Luminogens for Non-doped Organic Light-emitting Diodes

Han Nie,1 Zujin Zhao1a and Ben Zhong Tang1,2,3b 1State Key Laboratory of Luminescent Materials and Devices, South China University of Technology, Guangzhou 510640, China 2Department of Chemistry, The...
Han Nie, Zujin Zhao, Ben Zhong Tang
Material Matters, 2016, 11.1, 29
Keywords: Bacterial conjugations, Building blocks, Deposition, Electronics, Indicators, Organic electronics, Semiconductor, Solvents

Peer-Reviewed Papers


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