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798142 Sigma-Aldrich

Fluorescent nanodiamond

Nitrogen vacancy ~1.5ppm NV centers, 100 nm avg. part. size, 1 mg/mL in deionized water

Synonym: Diamond nanopowder, Nanodiamonds

  • Linear Formula C

  •  NACRES NA.23



Related Categories 06: C, Biomedical Materials, Carbon Nanomaterials, Fluorescent Nanodiamonds, Materials Science,
Quality Level   100
form   suspension
composition   Nitrogen vacancy, ~1.5ppm NV centers
concentration   1 mg/mL in deionized water
avg. part. size   100 nm
storage temp.   room temp


General description

Fluorescent nanodiamonds (FNDs) can be prepared by subjecting synthetic diamond nanocrystallites to helium ions. FND is biocompatible and its surface can be easily functionalized. It is a very useful tool in bioimaging mainly because the photons emitted from the defect centers of FND upon laser excitation can easily penetrate the tissue. The emission from FNDs is extremely stable. The average size of the FNDs is 100 nm.

In fluorescent nanodiamonds, the nitrogen vacancy centers in the diamond lattice provide the fluorescence; unlike the quantum dots or organic dyes, the color centers in these don’t photobleach or photoblink. These outstanding properties of fluorescent nanodiamonds along with their biocompatibility, large surface area etc. make them promising as bioimaging probes.

Product can be functionalized with carboxylic acid, hydroxyl, ketones, ethers, and/or hydrogen.


Potential uses of FNDs are as in vivo nanoprobe for bioimaging, cell labelling and cell tracking.

Safety & Documentation

Safety Information

NONH for all modes of transport
WGK Germany 
Flash Point(F) 
Not applicable
Flash Point(C) 
Not applicable


Certificate of Analysis (COA)

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Protocols & Articles


Fluorescent Nanodiamond Particles Containing Color Centers: Properties and Applications

Nanodiamond (ND) particles are increasingly being utilized as diagnostic, imaging, and therapeutic agents in biomedicine,1 for cryptography and quantum computing in quantum information processing, an...
Dr. Olga A. Shenderova
President, Adámas Nanotechnologies, Inc.
Keywords: Absorption, Clinical, Derivatizations, Diagnostic, Diffraction, Diffusion, Hormones, Infrared spectroscopy, Microscopy, Nucleic acid annealing, Purification, Reductions, Scanning electron microscopy, Sterilizations

Fluorescent Nanomaterials for Bioimaging: Consideration of Particle Brightess, Photostability, and Size

1 ARC Centre of Excellence for Nanoscale BioPhotonics & School of Science, RMIT University, Melbourne, VIC 3001, Australia 2 Adámas Nanotechnologies, Inc., 8100 Brownleigh Drive, Suite 120, Raleigh, ...
Keywords: Absorption, Cancer, Clinical, Confocal microscopy, Diffraction, Diffusion, Extinction coefficient, Infrared spectroscopy, Microscopy, Nanomaterials, Passive transport, Reductions, Scanning electron microscopy, Semiconductor

Functionalization of Fluorescent Nanodiamonds for Bioimaging

Fluorescent nanodiamonds (FNDs) exhibit distinct properties such as high biological compatibility, infinite photostability, absence of photoblinking, long fluorescence lifetime (>10 ns), and ease of ...
Marco Torelli,1 Nicholas Nunn,1 Olga Shenderova1,2

1Adámas Nanotechnologies, Inc.
2Department of Materials Science and Engineering, North Carolina State University, Raleigh, NC
Keywords: Amidations, Bacterial conjugations, Biotinylations, Centrifugation, Click chemistry, Detergents, Diagnostic, Electron spin resonance, Eliminations, Esterifications, Flow cytometry, Fluorescent microscopy, Gene expression, Infrared spectroscopy, Ligands, Microscopy, Nanomaterials, PEGylations, Polymerization reactions, Reductions, Sonication, Substitutions

Micro- and Nanofabricated Biomaterials for the Study of Cells and Microtissues

Phin Peng Lee, Karen E. Samy, Miquella G. Chavez, Alec Cerchiari, Tejal A. Desai* Department of Bioengineering and Therapeutic Sciences, University of California San Francisco, San Francisco, CA 9415...
Keywords: Absorption, Adhesion, Amplification, Apoptosis, Biomaterials, Cancer, Cell culture, Cell proliferation, Diffusion, Immobilization, Indicators, Infrared spectroscopy, Ligands, Magnetic resonance imaging, Materials Science, Microscopy, Molecular biology, Nanotechnology, Semiconductor, Solvents

Monodispersed Nanodiamonds and their Applications

Among various nanomaterials, nanoparticles of less than 10 nm size remain the most sought-after products. Their production, however, is a challenging task since the final structure and structural sta...
Dr. Olga A. Shenderova1,2,3

1Department of Materials Science and Engineering, North Carolina State University, Raleigh, NC, USA
2International Technology Center, Raleigh, NC, USA
3President, Adámas Nanotechnologies, Inc., Raleigh, NC, USA
Keywords: Adsorption, Antifungals, Chemical vapor deposition, Combustion, Cosmetics, Deposition, Electronics, Immobilization, Materials Science, Microscopy, Nanomaterials, Oxidations, Pharmaceutical, Purification, Reductions, Scanning electron microscopy, Solvents, Transmission electron microscopy

Peer-Reviewed Papers


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