808628 Sigma-Aldrich

Gold nanoparticles

5 nm diameter, biotin terminated, PEG 5000 coated, OD 50, dispersion in H2O

Synonym: Biotin Gold



Related Categories 79: Au, Biomedical Materials, Functionalized Gold Nanoparticles, Gold Nanoparticles, Materials Science,
Quality Level   100
material   PEG 5000
form   dispersion in H2O
packaging   pkg of 0.5 mL
OD   50
diameter   5 nm
surface area   61.8 m2/g
pH   5-7
density   1.00 g/cm3
λmax   513-517 nm
functional group   biotin
storage temp.   2-8°C


General description

Gold nanoparticles PEG 5000 biotin terminated.


Biotin functionalized gold nanoparticles are suitable for binding of streptavidin labelled conjugates. The gold nanoparticle label allows for straightforward detection of streptavidin by measuring the increase in absorbance of the sample upon binding. The absorption maximum is gold nanoparticle size dependent, and ranges from 515-520 nm for a 5 nm particle to 572 nm for a 100 nm particle.

Gold nanoparticles 5 nm diameter, biotin terminated, PEG 5000 coated, OD 50, dispersion in H2O can be used as a theranostic agent for potential usage in cancer therapy and treatment of COVID-19. It can also be used in the detection of pathogens for biosensing applications. AuNPs may be used to prepare SARS-CoV-2 conjugate for COVID-19 detection using lateral flow immunoassay technique.

Safety & Documentation

Safety Information

NONH for all modes of transport
WGK Germany 
Flash Point(F) 
Not applicable
Flash Point(C) 
Not applicable


Certificate of Analysis (COA)

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Protocols & Articles


2D Materials Matter: A Perspective on Biosensing Applications

1 Department of Materials Science and Engineering, The Pennsylvania State University, University Park, PA 16802, USA 2 School of Electrical Engineering and Computer Science, The Pennsylvania State Un...
Keywords: Adsorption, Atomic absorption spectroscopy, Cancer, Catalysis, Chemical vapor deposition, Clinical, Deposition, Immobilization, Inflammation, Ion-exchange chromatography, Lithiations, Materials Science, Metabolites, Nanomaterials, Neurotransmitters, Oxidations, Raman spectroscopy, Spectroscopy, Transduction

Increasing the Sensitivity of Lateral Flow Diagnostic Assays with Ultra-Bright Gold Nanoshell Reporters

Lateral flow assays (also known as immunochromatographic assays) detect or quantify biomolecules in complex samples including blood, urine, saliva, or other fluids to diagnose a variety of medical co...
Keywords: Absorption, Adsorption, Bacterial conjugations, Centrifugation, Deposition, Detergents, Diagnostic, Filtration, Flow cytometry, Hormones, Hydration reaction, Immobilization, Ligands, Microscopy, Raman spectroscopy, Scanning electron microscopy, Spectroscopy, Transmission electron microscopy

Peer-Reviewed Papers


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