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808709 Sigma-Aldrich

Gold nanoparticles

10 nm diameter, biotin terminated, PEG 5000, OD 50, dispersion in H2O

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Properties

Related Categories 79: Au, Biomedical Materials, Functionalized Gold Nanoparticles, Gold Nanoparticles, Materials Science,
Quality Level   100
material   PEG 5000
form   dispersion in H2O
  nanoparticles
composition   , 2.99E+14 particles/mL
packaging   pkg of 0.5 mL
concentration   3.04 mg/mL in H2O
OD   50
diameter   10 nm
surface area   30.8 m2/g
pH   5-7
density   1.00 g/cm3
λmax   515-520 nm
functional group   biotin
storage temp.   2-8°C

Description

General description

Gold nanoparticles PEG 5000 biotin terminated.

Application

Biotin functionalized gold nanoparticles are suitable for binding of streptavidin labelled conjugates. The gold nanoparticle label allows for straightforward detection of streptavidin by measuring the increase in absorbance of the sample upon binding. The absorption maximum is gold nanoparticle size dependent, and ranges from 515-520 nm for a 5 nm particle to 572 nm for a 100 nm particle.

Gold nanoparticles 10 nm diameter, biotin terminated, PEG 5000, OD 50, dispersion in H2O can be used as a theranostic agent for potential usage in cancer therapy and treatment of COVID-19. It can also be used in the detection of pathogens for biosensing applications. AuNPs may be used to prepare SARS-CoV-2 conjugate for COVID-19 detection using lateral flow immunoassay technique.

Legal Information

Product of Cytodiagnostics, Inc.

Safety & Documentation

Safety Information

RIDADR 
NONH for all modes of transport
Flash Point(F) 
Not applicable
Flash Point(C) 
Not applicable

Documents

Certificate of Analysis (COA)

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Protocols & Articles

Articles

Increasing the Sensitivity of Lateral Flow Diagnostic Assays with Ultra-Bright Gold Nanoshell Reporters

Lateral flow assays (also known as immunochromatographic assays) detect or quantify biomolecules in complex samples including blood, urine, saliva, or other fluids to diagnose a variety of medical co...
Keywords: Absorption, Adsorption, Bacterial conjugations, Centrifugation, Deposition, Detergents, Diagnostic, Filtration, Flow cytometry, Hormones, Hydration reaction, Immobilization, Ligands, Microscopy, Raman spectroscopy, Scanning electron microscopy, Spectroscopy, Transmission electron microscopy

Peer-Reviewed Papers
15

References

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