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81260 Sigma-Aldrich

Poly(ethylene glycol)

average Mn 6,000

Synonym: PEG

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Properties

Related Categories Essential Chemicals, Materials Science, PEG and Oligo Ethylene Glycol, Poly(ethylene glycol), Poly(ethylene glycol) (PEG) and PEG Solutions,
Quality Level   300
form   flakes
mol wt   Mn 5,000-7,000
  average Mn 6,000
pH   4.5-7.5
mp   60-63 °C
Ω-end   hydroxyl
α-end   hydroxyl
SMILES string   C(CO)O
InChI   1S/C2H6O2/c3-1-2-4/h3-4H,1-2H2
InChI key   LYCAIKOWRPUZTN-UHFFFAOYSA-N

Description

General description

Polyethylene glycol (PEG) is a hydrophilic polymer. It can be easily synthesized by the anionic ring opening polymerization of ethylene oxide, into a range molecular weights and variety of end groups. When crosslinked into networks PEG can have high water content, forming "hydrogels". Hydrogel formation can be initiated by either crosslinking PEG by ionizing radiation or by covalent crosslinking of PEG macromers with reactive chain ends. PEG is a suitable material for biological applications because it does not trigger an immune response.

Application

It has been used to modify therapeutic proteins and peptides to increase their solubility.
Photopolymerized PEG hydrogels have emerging applications in the fabrication of bioactive and immunoisolating barriers for encapsulation of cells.

Packaging

1 kg in poly bottle

5 kg in glass bottle

Safety & Documentation

Safety Information

Personal Protective Equipment 
RIDADR 
NONH for all modes of transport
WGK Germany 
WGK 1
Flash Point(F) 
Not applicable
Flash Point(C) 
Not applicable

Documents

Certificate of Analysis (COA)

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Single- & multi-channel pipettes from BRAND
Protocols & Articles

Articles

Polyethylene Glycol (PEG) Selection Guide

Poly(ethylene glycol) (PEG) is a synthetic, hydrophilic, biocompatible polymer with widespread use in biomedical and other applications. PEGs are synthesized using a ring-opening polymerization of et...
Keywords: Adhesion, Bacterial conjugations, Click chemistry, Molecular biology, PEGylations, Polymerization reactions, Ring-opening polymerization

Peer-Reviewed Papers
15

References

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