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900210 Aldrich

Regenerez® Poly(glycerol sebacate) Resin

Synonym: PGS, Poly(glycerol sebacic acid)

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Properties

Related Categories Biodegradable Polymers, Materials Science, Polyanhydrides and Polyesters, Polyesters, Polymer Science,
form   paste
transition temp   flash point >230 °F
storage temp.   −20°C

Description

Features and Benefits

• Bioresorbable.
• Comprised of naturally occurring metabolites (glycerol and sebacic acid).
• Tunable mechanical properties.
• Versatile platform for further modification.
• Closely simulates modulus of human tissue.
• Enables healing without harmful immune response.

Legal Information

U.S. Patent No. 9,359,472.

Regenerez is a registered trademark of The Secant Group, LLC

Application

Regenerez® Poly(glycerol sebacate) is a bioresorbable elastomer. The physical properties can be tuned from an elastomer to a thermoset(U.S. Patent No. 9.359,472) by curing PGS to the desired level of cross-linking. The inherent elastomeric properties of PGS can be used in a variety of applications in regenerative medicine and tissue engineering.

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Safety & Documentation

Safety Information

RIDADR 
NONH for all modes of transport
WGK Germany 
3
Flash Point(F) 
>230 °F
Flash Point(C) 
>110 °C
Protocols & Articles

Articles

Biomaterials Tutorial

Biocompatible Polymers Biodegradable Polymers Crosslinkers Biocompatible Inorganic Materials Supramolecular Chemistry
Keywords: Agriculture, Antimicrobials, Biomaterials, Ceramics, Chromatography, Cosmetics, Degradations, Diffusion, Environmental, Genomics, Germination, Nanomaterials, Oxidations, Petrochemical, Pharmaceutical, Polymerization reactions, Proteomics, Reductions

Poly(Glycerol Sebacate) in Tissue Engineering and Regenerative Medicine

Yadong Wang,1 Steven Lu,2 Peter Gabriele,2 Jeremy J. Harris2* 1Department of Bioengineering, University of Pittsburgh, Pittsburgh, PA 15261 USA 2Research and Development, The Secant Group, LLC, Telfo...
Yadong Wang, Steven Lu, Peter Gabriele, Jeremy J. Harris
Material Matters, 2016, 11.3
Keywords: Antimicrobials, Biomaterials, Building blocks, Cardiovascular, Clinical, Confocal microscopy, Degradations, Ligands, Metabolites, Microscopy, Oxidations, Pharmaceutical, Polymerization reactions, Positron Emission Tomography, Reversed-phase chromatography, Solvents, Titrations, transformation

Peer-Reviewed Papers
15

References

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