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900914 Sigma-Aldrich

Methyltetrazine-NHS ester

≥95%

  • CAS Number 1644644-96-1

  • Empirical Formula (Hill Notation) C15H13N5O4

  • Molecular Weight 327.29

  •  MDL number MFCD28334557

  •  NACRES NA.22

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Description

Application

Methyltetrazine-NHS ester has an N-hydroxysuccinimide (NHS) ester that can be reacted with primary amines and a methyltetrazine, which is reactive to trans-cyclooctenes. The NHS ester reacts with primary amines (e.g. side chain of lysine residues or aminosilane-coated surfaces) at neutral or slightly basic pH to form covalent bonds. The short spacer arm adds minimal mass to modified molecules (230.2 daltons). It is generally used in click chemistry applications in bioconjugate chemistry.

Packaging

100 mg in glass insert

Safety & Documentation

Safety Information

RIDADR 
NONH for all modes of transport

Documents

Certificate of Analysis (COA)

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Protocols & Articles
Peer-Reviewed Papers
15

References

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