• USA Home
  • 901304 - Polyester bis-MPA dendron 16 NHBoc, 1 thiol (core)

EMAIL THIS PAGE TO A FRIEND
901304 Sigma-Aldrich

Polyester bis-MPA dendron 16 NHBoc, 1 thiol (core)

generation 4

Synonym: Bis-MPA dendron, PFd-G4-Thiol-NH-BOC

  • Empirical Formula (Hill Notation) C205H334N16O94S

  • Molecular Weight 4558.96

  •  NACRES NA.23

Purchase

Properties

Related Categories Dendrimers, Dendrons, Materials Science, Nanomaterials
Quality Level   100
description   16 NHBoc, 1 thiol (core)
form   solid
mol wt   generation 4
no. Surface Groups   16
color   white to off-white
functional group   thiol (core)
storage temp.   −20°C

Description

General description

• Polymer architecture: Dendron
• End Group Functionality: Boc-protected amine
• Boc: tert-Butyloxycarbonyl
• Bis-MPA: 2,2-Bis(hydroxymethyl)propionic acid

Application

Bis-MPA (or 2,2-Bis(methylol)propionic acid) is an aliphatic, pro-chiral molecule comprised of two hydroxyls and one carboxylic group that has been used in the synthesis of many different types of polymers. Dendrons synthesized from bis-MPA are biodegradable and have low cytotoxicity, making them well suited for use in biological research applications. These materials have been used in many applications such as signal amplification in bioassays and in drug delivery applications. After Boc deprotection, amine-functionalized dendrons can be readily used in EDC or DCC coupling reactions with carbonyl-containing compounds to yield highly functionalized materials for a variety of biomedical applications. Additionally, the thiol-core can be readily conjugated via a thiol-ene click reaction, Michael addition reactions, or disulfide exchange.

Safety & Documentation

Safety Information

RIDADR 
NONH for all modes of transport
WGK Germany 
WGK 3
Flash Point(F) 
Not applicable
Flash Point(C) 
Not applicable

Documents

Certificate of Analysis (COA)

Please Enter a Lot Number
Protocols & Articles
Peer-Reviewed Papers
15

References

Related Products

Technical Service:

Our team of scientists has experience in all areas of research including Life Science, Material Science, Chemical Synthesis, Chromatography, Analytical and many others.

Bulk Ordering & Pricing:

Need larger quantities for your development, manufacturing or research applications?