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901568 Sigma-Aldrich

Bromo-PEG3-acid

  • CAS Number 782475-35-8

  • Empirical Formula (Hill Notation) C9H17BrO5

  • Molecular Weight 285.13

  •  MDL number MFCD22574820

  •  NACRES NA.22

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Properties

form   liquid
storage temp.   −20°C

Description

Application

Bromo-PEG3-acid is a heterobifunctional, PEGylated crosslinker featuring a bromo group at one end and a carboxyl group at the other. The hydrophillic PEG linker facilitates solubility in biological applications. Bromo-PEG3-acid can be used for bioconjugation or as a building block for synthesis of small molecules, conjugates of small molecules and/or biomolecules, or other tool compounds for chemical biology and medicinal chemistry that require ligation. Examples of applications include its synthetic incorporation into antibody-drug conjugates or proteolysis-targeting chimeras (PROTAC® molecules) for targeted protein degradation.

This is a crosslinker with a bromo group on one end and a carboxyl group on the other end. The compound contains three PEG units to help improve solubility.

Legal Information

PROTAC is a registered trademark of Arvinas Operations, Inc., and is used under license

Safety & Documentation

Safety Information

RIDADR 
NONH for all modes of transport
WGK Germany 
WGK 3

Documents

Certificate of Analysis (COA)

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Protocols & Articles
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901832 Pomalidomide-PEG6-NH2 hydrochloride, ≥98%
901831 Pomalidomide-PEG5-NH2 hydrochloride
901830 Pomalidomide-PEG4-NH2 hydrochloride, ≥95%
901860 (S,R,S)-AHPC-PEG6-NH2 hydrochloride, ≥95%
903434 Pomalidomide-PEG6-butyl azide, ≥95%
903442 Pomalidomide-PEG6-butyl iodide, ≥95%
903833 Pomalidomide-PEG2-azide
903825 Pomalidomide-PEG1-azide
903957 (S,R,S)-AHPC-PEG1-azide
904651 (S,R,S)-AHPC-PEG3-azide, ≥95%
904724 Pomalidomide-PEG2-butyl iodide, ≥95%
904708 Pomalidomide-C6-PEG3-butyl iodide, ≥95%
904678 Pomalidomide-PEG3-azide
904686 Pomalidomide-C6-PEG3-butyl azide, ≥95%
904813 (S,R,S)-AHPC-PEG2-azide
904821 (S,R,S)-AHPC-C6-PEG3-butyl azide, ≥95%
904880 Pomalidomide-C6-PEG1-C3-PEG1-butyl azide, ≥95%
904872 Pomalidomide-PEG2-butyl azide, ≥95%
904864 (S,R,S)-AHPC-PEG6-butyl azide, ≥95%
905178 (S,R,S)-AHPC-C6-PEG1-C3-PEG1-butyl azide, ≥95%
905275 (S,R,S)-AHPC-PEG6-butyl amine hydrochloride, ≥95%
905216 (S,R,S)-AHPC-PEG2-butyl azide, ≥95%
905232 (S,R,S)-AHPC-C6-PEG3-butyl amine hydrochloride, ≥95%
905224 Pomalidomide-PEG6-butyl amine hydrochloride, ≥95%
905208 Pomalidomide-C6-PEG3-butyl amine hydrochloride, ≥98%
905399 (S,R,S)-AHPC-PEG2-butyl chloride
905380 (S,R,S)-AHPC-C6-PEG3-butyl chloride, ≥95%
905402 (S,R,S)-AHPC-C6-PEG1-C3-PEG1-butyl chloride, 95%
906050 Pomalidomide-C6-PEG1-C3-PEG1-butyl iodide, ≥95%
906123 (S,R,S)-AHPC-PEG2-butyl amine hydrochloride
907677 (S,R,S)-AHPC-PEG6-butyl chloride
910066 6-(2-(2-(Oct-7-yn-1-yloxy)ethoxy)ethoxy)hexanoic acid, ≥90%

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