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901800 Sigma-Aldrich

Fluorescent nanodiamond

nitrogen vacancy ~3 ppm NV centers, 140 nm avg. part. size, carboxylic acid functionalized, PEG 3000 coated, 1 mg/mL in deionized water

Synonym: Fluorescent nanoparticles, Nanodiamonds

  •  NACRES NA.23

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Properties

Related Categories 06: C, Biomedical Materials, Carbon Nanomaterials, Fluorescent Nanodiamonds, Materials Science,
form   nanoparticles
composition   nitrogen vacancy, ~3 ppm NV centers
concentration   1 mg/mL in deionized water
avg. part. size   140 nm

Description

General description

Fluorescent nanodiamond (nitrogen vacancy ~3 ppm NV centers, 140 nm avg. part. size, carboxylic acid functionalized, PEG 3000 coated, 1 mg/mL in deionized water), a biocompatible carbon-based nanomaterial, has interesting properties like excellent photostability, low toxic and facile surface functionalizability. It can be used for a variety of biological applications.

Application

Nanodiamonds (NDs) containing NV color centres exhibit fluorescence in red/near infra-red (NIR) region. The fluorescence in NDs originates from nitrogen vacancies and, unlike quantum dots and organic dyes, NDs do not photobleach. Fluorescent NDs find applications in background-free imaging, flow cytometry, super-resolution imaging etc. Our PEG coated carboxyl functionalized NDs are well suited for attachment of biomolecules using EDC chemistry. The presence PEG spacer on NDs reduces the steric hindrance among the biomolecules.

Safety & Documentation

Safety Information

RIDADR 
NONH for all modes of transport
WGK Germany 
WGK 1
Flash Point(F) 
Not applicable
Flash Point(C) 
Not applicable

Documents

Certificate of Analysis (COA)

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Protocols & Articles

Articles

Fluorescent Nanomaterials for Bioimaging: Consideration of Particle Brightess, Photostability, and Size

1 ARC Centre of Excellence for Nanoscale BioPhotonics & School of Science, RMIT University, Melbourne, VIC 3001, Australia 2 Adámas Nanotechnologies, Inc., 8100 Brownleigh Drive, Suite 120, Raleigh, ...
Keywords: Absorption, Cancer, Clinical, Confocal microscopy, Diffraction, Diffusion, Extinction coefficient, Infrared spectroscopy, Microscopy, Nanomaterials, Passive transport, Reductions, Scanning electron microscopy, Semiconductor

Peer-Reviewed Papers
15

References

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