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904759 Sigma-Aldrich

Polyethylenimine, branched

average Mw ~270,000 by LS

Synonym: PEI

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Properties

Related Categories Branched PEI, Hydrophilic Polymers, Materials Science, Poly(2-oxazoline) and Polyethylenimine (PEI), Polyethylenimine (PEI),
description   Identity:Conforms to structure
assay   >93% (KFT)
form   liquid
mol wt   ~90 kDa by LS
  average Mw ~270,000 by LS
color   colorless to pale yellow
bp   250 °C (lit.)
SMILES string   C1CN1
InChI   1S/C2H5N/c1-2-3-1/h3H,1-2H2
InChI key   NOWKCMXCCJGMRR-UHFFFAOYSA-N

Description

Application

Branched polyethyleneimine (PEI) is widely used in many applications due to its polycationic character. Unlike its linear equivalent, branched PEI contains primary, secondary, and tertiary amines. Primarily utilized in industrial applications, high molecular weight PEI has been used as a flocculating agent, textile coating, adhesion promoter, enzyme carrier, and as a material for CO2 capture.

Polyethylenimine, branched (PEI) is a hydrophilic polymer and a gene carrier, which can be conjugated with dextran to enhance the stability of polycationic vectors. It is also used in the preparation of cationic poly(lactic-co-glycolic acid) (PLGA) nanoparticles for potential usage in gene therapy. PEI can also be grafted on polyacrylonitrile (PAN) fiber membrane for the removal of hexavalent chromium (VI) from wastewater.

Safety & Documentation

Safety Information

Symbol 
Signal word 
Warning
Hazard statements 
WGK Germany 
WGK 2
Protocols & Articles

Articles

Nanoparticle-Based Drug and Gene Delivery for Tumor Targeting

Department of Chemistry and Biochemistry, Faculty of Engineering, Kyushu University, Japan *E-mail: ykatatcm@mail.cstm.kyushu-u.ac.jp
Keywords: Amplification, Angiogenesis, Biochemistry, Cancer, Cardiovascular, Clinical, Diagnostic, Electron spin resonance, Enzyme activity, Gene expression, Genetic, Infrared spectroscopy, Reductions, Transcription

Peer-Reviewed Papers
15

References

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