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905283 Sigma-Aldrich

(6-Aminohexyl)triphenylphosphonium bromide hydrobromide

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≥95%

Synonym: Aminohexane TPP mitochondrial tag, Mitochondria-targeting probe building block, Phosphonium lipocation tag

  • Empirical Formula (Hill Notation) C24H29BrNP · xHBr

  • Molecular Weight 442.37 (free base basis)

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Description

Application

Mitochondria perform several functions in the cell, and dysfunction has been implicated in various organ systems and disease states, including neurodegenerative disorders and cancers. The targeting of small molecules to the mitochondria can help to probe and better understand this relationship. This aminohexane triphenylphosphine (TPP) tag is conjugated to small molecules to localize them to the mitochondria in cells where the TPP cations facilitate both cellular uptake and accumulation in the mitochondria.

Other Notes

Development of organelle-targetable europium complex probes for time-gated luminescence imaging of hypochlorous acid in live cells and animals

Targeting lipophilic cations to mitochondria

Photoswitchable polyfluorophores based on perylenemonoimide-dithienylethene conjugates as super-resolution MitoTrackers

Safety & Documentation

Safety Information

Safety Information for this product is unavailable at this time.

Documents

Certificate of Analysis (COA)

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Protocols & Articles
Peer-Reviewed Papers
15

References

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