905607 Sigma-Aldrich

(R)-Tol-BINAP Pd G3


Synonym: (R)-Tol-BINAP G3 palladacycle, (R)-Tol-BINAP palladacycle

  • Empirical Formula (Hill Notation) C61H53NO3P2PdS

  • Molecular Weight 1048.51



Related Categories Catalysis and Inorganic Chemistry, Chemical Synthesis, Homogeneous Pd Catalysts, Palladium Catalysts
assay   ≥95%
form   powder or crystals
reaction suitability   core: palladium
  reaction type: Buchwald-Hartwig Cross Coupling Reaction
  reaction type: Heck Reaction
  reaction type: Hiyama Coupling
  reaction type: Negishi Coupling
  reaction type: Sonogashira Coupling
  reaction type: Stille Coupling
  reaction type: Suzuki-Miyaura Coupling
  reagent type: catalyst
reaction type: Cross Couplings
mp   >300 °C
functional group   phosphine
SMILES string   PC1=CC=C2C(C=CC=C2)=C1C3=C(C)C=CC4=C3C=CC=C4.NC(C=CC=C5)=C5C6=C([Pd]OS(C)(=O)=O)C=CC=C6.[Tol2].[Tol2].P


General description

(R)-Tol-BINAP Pd G3 is a third generation (G3) Buchwald precatalyst. It is air, moisture and thermally stable and is highly soluble in a wide range of common organic solvents. It has long life in solutions. Qphos Pd G3 is an excellent reagent for palladium catalyzed cross-coupling reactions. Some of its unique features include lower catalyst loadings, shorter reaction time, efficient formation of the active catalytic species and accurate control of ligand: palladium ratio.


(R)-Tol-BINAP Pd G3 can be used in the stereoselective synthesis of perfluoroalkyl-substituted enones by reacting four components, alkynes, iodoperfluoroalkanes, (hetero)arylboronic acids, and carbon monoxide.

Other Notes

Pd-Catalyzed Carbonylative Carboperfluoroalkylation of Alkynes. Through-Space 13C–19F Coupling as a Probe for Configuration Assignment of Fluoroalkyl-Substituted Olefins

Safety & Documentation

Safety Information

WGK Germany 
Flash Point(F) 
Not applicable
Flash Point(C) 
Not applicable


Certificate of Analysis (COA)

Please Enter a Lot Number
Protocols & Articles
Peer-Reviewed Papers


Related Products

related product

Product #


Add to Cart

900534 (t-Bu)PhCPhos Pd G3, ≥95%
900620 4MetBuXPhos Pd G3
900621 CyJohnPhos Pd G3, 95%
901219 VPhos Pd G3, 95%
903027 QPhos Pd G3
763381 XPhos Pd G3, 98%
776246 SPhos Pd G3, 97%
776106 AdBrettPhos Pd G3
794228 N-XantPhos Pd G3, 95%

Technical Service:

Our team of scientists has experience in all areas of research including Life Science, Material Science, Chemical Synthesis, Chromatography, Analytical and many others.

Bulk Ordering & Pricing:

Need larger quantities for your development, manufacturing or research applications?