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909734 Sigma-Aldrich

1-Phenyl-2-((trifluoromethyl)sulfonyl)propan-1-one

  • CAS Number 155201-05-1

  • Empirical Formula (Hill Notation) C10H9F3O3S

  • Molecular Weight 266.24

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Properties

Related Categories C-C Bond Formation, Chemical Synthesis, Other Synthetic Reagents for C-C Bond Formation, Synthetic Reagents
reaction suitability   reaction type: C-C Bond Formation
storage temp.   −20°C

Description

Application

1-Phenyl-2-((trifluoromethyl)sulfonyl)propan-1-one is part of a suite of reagents developed by the Li group for late-stage functionalization of pharmaceutically relevant compounds. The reagents serve as precursors to alkyl radicals generated under light mediated, redox-neutral and catalyst free conditions for use in the Minisci alkylation of aromatics.

Other Notes

Catalyst-Free and Redox-Neutral Innate Trifluoromethylation and Alkylation of Aromatics Enabled by Light

Safety & Documentation

Safety Information

WGK Germany 
WGK 3
Flash Point(F) 
Not applicable
Flash Point(C) 
Not applicable

Documents

Certificate of Analysis (COA)

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Protocols & Articles
Peer-Reviewed Papers
15

References

Related Products

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Description

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909726 2-((Difluoromethyl)sulfonyl)-1-phenylpropan-1-one, ≥95%

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