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910813 Sigma-Aldrich

mPEG24-NHS

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Synonym: Methoxypolyethylene glycol acetic acid N-succinimidyl ester, mPEG NHS

  • CAS Number 174569-25-6

  • Empirical Formula (Hill Notation) C56H107NO29

  • Molecular Weight 1258.44

  •  MDL number MFCD28385538

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Properties

Related Categories Materials Science, Monofunctional PEGs, NHS Ester, Poly(ethylene glycol) and Poly(ethylene oxide), Polymer Science,
assay   95% (HPLC)
form   solid
mol wt   average Mn 1,250 (by NMR)
color   white to off-white
Ω-end   NHS ester
α-end   methoxy
polymer architecture   shape : linear
functionality : monofunctional
reaction suitability   reagent type: chemical modification reagent
reactivity: amine reactive
storage temp.   −20°C

Description

Application

Polyethylene glycols (PEGs) are FDA approved hydrophilic polymers. They are non-toxic, non-immunogenic and non-antigenic, and are widely used in a variety of biomedical applications such as bioconjugation, drug delivery, surface functionalization, and tissue engineering. PEG-NHS is an amine reactive PEG that can react to amino groups of lysine(s) on proteins or other biologics; reaction occurs at room temperature in <1hr at pH 7-8. Stable linker between PEG and NHS ester.

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