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911593 Sigma-Aldrich

NanoFabTx microfluidic - nano

device kit for synthesis of 100-200 nm nanoparticles

Synonym: Microfluidic kit, NanoFabTx device kit, Nanoformulation, Nanoparticle

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Properties

Related Categories Biodegradable Polymers, Materials Science, NanoFabTx Device Kits, NanoFabTx Formulation Kits, PLGA Microspheres and Nanoparticles,
description   Microfludic device kit for synthesizing nanparticles

Kit components :
• Microfluidic chip x 1
• Tubings and accessories

Description

Application

• Microfluidic formulation development for enhancing drug bioavailability
• Optimization of drug encapsulation and loading efficiency in nanoparticles and liposomes
• Selection of optimal nanoparticle and liposome size
• Optimized to make 100-200 nanoparticles or liposomes
• Step-by-step microfluidic-based protocols developed and tested by our formulation scientists

NanoFabTx Microfluidic - nano device kit is designed to work with NanoFabTx - nano reagent kits (please visit www.sigmaaldrich.com/nanofabtx <http://www.sigmaaldrich.com/nanofabtx>) and can be used to create drug-encapsulated polymeric nanoparticles or liposomes with narrow size dispersity and high batch-to-batch consistency. The device kit includes a comprehensive protocol, pre-assembled microfluidic chip manifold, tubing, and required accessories and is compatible with either the Dolomite microfluidics system or a standard syringe pump (compatible microfluidics system or syringe pump required separately).
Microfluidic-based synthesis is a powerful tool for fabricating size-controlled drug delivery particles. The chip geometries and flow parameters enable facile synthesis of monodispersed particles with minimum batch-to-batch variance. Microfluidics allows scalable synthesis of particles, and rapid formulation screening.

Other Notes

This kit was developed and tested in partnership with Dolomite Microfluidics. For compatible pumps and microfluidic systems, please visit , Dolomite for more information.

Legal Information

NANOFABTX is a trademark of Sigma-Aldrich Co. LLC

Safety & Documentation

Safety Information

Safety Information for this product is unavailable at this time.
Protocols & Articles

Articles

Biomaterials Tutorial

Biocompatible Polymers Biodegradable Polymers Crosslinkers Biocompatible Inorganic Materials Supramolecular Chemistry
Keywords: Agriculture, Antimicrobials, Biomaterials, Ceramics, Chromatography, Cosmetics, Degradations, Diffusion, Environmental, Genomics, Germination, Nanomaterials, Oxidations, Petrochemical, Pharmaceutical, Polymerization reactions, Proteomics, Reductions

Flash NanoPrecipitation

The principle of Flash NanoPrecipitation (FNP) was first described in 2003 by Johnson and Prud’homme as a novel method to generate highly loaded nanoparticles through a rapid mixing and precipitation...
Keywords: Absorption, Adsorption, Bacterial conjugations, Calorimetry, Cancer, Crystallization, Degradations, Diagnostic, Diagnostic Imaging, Environmental, Hormones, Ligands, Magnetic resonance imaging, Oncology, Pesticides, Positron Emission Tomography, Precipitation, Solvents, Vitamins

Peer-Reviewed Papers
15

References

Related Products

Technical Service:

Our team of scientists has experience in all areas of research including Life Science, Material Science, Chemical Synthesis, Chromatography, Analytical and many others.

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