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911860 Sigma-Aldrich

NanoFabTx microfluidic - micro

device kit for synthesis of 1-5 μm particles

Synonym: Microfluidic kit, Microparticle, Nanoformulation

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Properties

description   Microfludic device kit for synthesizing 1-5 μm microparticles

Kit components :
• Microfluidic chip x 1
• Tubings and accessories

Description

Application

• Screening the optimal microformulation for enhancing drug bioavailability
• Selection of optimal size
• Optimization of drug encapsulation and loading efficiency

• Step-by-step microfluidic-based protocols developed and tested by our formulation scientists
• Flexible synthesis tool to create uniform and reproducible microparticles
• Optimized to make 1-5 μm microparticles

NanoFabTx microfluidic - micro is a ready to use microfluidic nanoformulation kit for the synthesis of drug delivery microparticles. This hardware kit includes a pre-assembled microfluidic chip, tubing and required accessories. NanoFabTx microfluidic - micro is a complete microfluidic setup that is ready for connection with a pump system to conduct microparticle synthesis experiments. Reagent kit (NanoFabTx PLGA-micro, for synthesis of 1-5 μm particles) is available to pair with this microfluidic kit for precise fabrication of nanoparticles.
Microfluidic system is a powerful tool for fabricating drug delivery particles. The well controlled chip geometries and flow parameters enable facile synthesis of monodispersed particles with minimum batch-to-batch variance. It allows rapid production of micro/ nano-particles, and reduce the time for screening optimal carriers for drug delivery.

Other Notes

This kit was developed and tested in partnership with Dolomite Microfluidics. For compatible pumps and microfluidic systems, Please visit: Dolomite for more information

Legal Information

NANOFABTX is a trademark of Sigma-Aldrich Co. LLC

Safety & Documentation

Safety Information

Safety Information for this product is unavailable at this time.

Documents

Certificate of Analysis (COA)

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Protocols & Articles

Articles

Flash NanoPrecipitation

The principle of Flash NanoPrecipitation (FNP) was first described in 2003 by Johnson and Prud’homme as a novel method to generate highly loaded nanoparticles through a rapid mixing and precipitation...
Keywords: Absorption, Adsorption, Bacterial conjugations, Calorimetry, Cancer, Crystallization, Degradations, Diagnostic, Diagnostic Imaging, Environmental, Hormones, Ligands, Magnetic resonance imaging, Oncology, Pesticides, Positron Emission Tomography, Precipitation, Solvents, Vitamins

Peer-Reviewed Papers
15

References

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