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912212 Sigma-Aldrich

NanoFabTx(TM) PLGA-Micro

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for synthesis of 10-30 um particles

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Properties

storage temp.   2-8°C

Description

Application

Poly(lactic-co-glycolic acid) (PLGA) is a biocompatible and biodegradable polymer that has been approved by the FDA and the EMA for biomedical and pharmaceutical applications. PLGA based nanoparticles have been widely used as drug delivery systems for different types of therapeutic molecules, to achieve controlled drug release.NanoFabTx(TM) PLGA-Micro is a ready-to-use nanoformulation kit for the synthesis of 10 to 30 um particles. This kit includes PLGA and stabilizer to make PLGA microparticles using microfluidics method. Drug molecules can be formulated into particles for drug delivery researches and applications. Protocols are provided for the facile fabrication of empty and drug loaded microparticles.

Features and Benefits

Key Features:
• Step-by-step microfluidic-based protocols developed and tested by our formulation scientists
• Flexible synthesis tool to create uniform and reproducible microparticles
• Optimized to make 10-30 μm microparticles

Applications:
• Screening the optimal micro formulation for enhancing bioavailability
• Selection of optimal size
• Optimization of drug encapsulation and loading efficiency

Legal Information

NanoFabTx is a trademark of Sigma Aldrich Co. LLC

Safety & Documentation

Safety Information

Safety Information for this product is unavailable at this time.

Documents

Certificate of Analysis (COA)

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Protocols & Articles

Articles

Flash NanoPrecipitation

The principle of Flash NanoPrecipitation (FNP) was first described in 2003 by Johnson and Prud’homme as a novel method to generate highly loaded nanoparticles through a rapid mixing and precipitation...
Keywords: Absorption, Adsorption, Bacterial conjugations, Calorimetry, Cancer, Crystallization, Degradations, Diagnostic, Diagnostic Imaging, Environmental, Hormones, Ligands, Magnetic resonance imaging, Oncology, Pesticides, Positron Emission Tomography, Precipitation, Solvents, Vitamins

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Technical Service:

Our team of scientists has experience in all areas of research including Life Science, Material Science, Chemical Synthesis, Chromatography, Analytical and many others.

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