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914339 Sigma-Aldrich

Fmoc-L-Lys(Nvoc)-OH

New

≥98%

Synonym: (S)-2-(((9H-Fluoren-9-yl)methoxy)carbonylamino)-6-((4,5-dimethoxy-2-nitrobenzyloxy)carbonylamino)hexanoic acid, N2-(((9H-Fluoren-9-yl)methoxy)carbonyl)-N6-(((4,5-dimethoxy-2-nitrobenzyl)oxy)carbonyl)-L-lysine, Lysine with photoremovable NVOC, Photocaged amino acid, Photocleavable lysine derivative

  • CAS Number 150571-28-1

  • Empirical Formula (Hill Notation) C31H33N3O10

  • Molecular Weight 607.61

  •  MDL number MFCD08064317

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Properties

Related Categories Chemical Biology, Chemical Synthesis, Lysine Derivatives, New Products for Chemical Synthesis, Peptide Synthesis and Peptide Chemistry,
Quality Level   100
assay   ≥98%
form   powder
mp   108 °C (decomp.)
storage temp.   2-8°C

Description

Application

Fmoc-L-Lys(Nvoc)-OH is a lysine derivative compatible with solid-phase peptide synthesis (SPPS). The photolabile, N-terminal protecting group nitroveratryloxycarbonyl (NVOC) can be cleaved by photolysis at 350 nm. Photocaged amino acids such as these are useful in the synthesis of photocleavable chemical tools for spatial and temporal control over released molecules in biological applications.

Other Notes

Total chemical synthesis of photoactivatable proteins for light-controlled manipulation of antigen-antibody interactions

In situ cell manipulation through enzymatic hydrogel photopatterning

Safety & Documentation

Safety Information

WGK Germany 
WGK 3
Flash Point(F) 
Not applicable
Flash Point(C) 
Not applicable

Documents

Certificate of Analysis (COA)

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Protocols & Articles
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