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914525 Sigma-Aldrich

o-Nitropiperonyl-O-tyrosine

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Synonym: (2S)-2-Amino-3-(4-(1-(6-nitrobenzo[d][1,3]dioxol-5-yl)ethoxy)phenyl)propanoic acid, Light-triggered decaging Tyr, NPY, Photo-controlled amino acid, Photocaged amino acid, Photocleavable tyrosine derivative

  • Empirical Formula (Hill Notation) C17H16N2O7

  • Molecular Weight 360.32

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Properties

Quality Level   100
form   powder
storage temp.   −20°C

Description

Application

o-Nitropiperonyl-O-tyrosine (NPY) is a photo-responsive unnatural amino acid (UAA) for spatiotemporal control of biological molecules or processes as reported by Kneuttinger et al. Irradiation with UV light decages the Tyr amino acid, freeing the residue or protein for biological activity. Tools such as NPY will find wide utility in light regulation of activity, allostery, and enzyme pathways.

Other Notes

Light Regulation of Enzyme Allostery through Photoresponsive Unnatural Amino Acids

Safety & Documentation

Safety Information

WGK Germany 
WGK 3
Flash Point(F) 
Not applicable
Flash Point(C) 
Not applicable

Documents

Certificate of Analysis (COA)

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Protocols & Articles
Peer-Reviewed Papers
15

References

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