• USA Home
  • 94324 - Deoxo-Fluor® solution

EMAIL THIS PAGE TO A FRIEND
94324 Sigma-Aldrich

Deoxo-Fluor® solution

~50% in toluene (NMR)

Synonym: Bis(2-methoxyethyl)aminosulfur trifluoride solution

Purchase

Properties

Related Categories Chemical Synthesis, Fluorination, Fluorination Reagents, Synthetic Reagents
InChI Key   APOYTRAZFJURPB-UHFFFAOYSA-N
form   liquid
concentration   ~50% in toluene (NMR)
color   clear yellow
storage temp.   2-8°C

Description

Application

Reactant for:
• Fluorination reactions
• Preparation of fluorinated catechols via Umpolung based nucleophilic deoxyfluorination
• Preparation of imidazole derivatives as CXCR3 antagonists
• Ring expansion reactions
• Synthesis of acyl azides from carboxylic acids
• Aldehydes or ketones from carboxylic acids and Grignard reagents via in situ generation of Weinreb amides

Other Notes

Fluorinating agent with high thermal stability

Legal Information

Deoxo-Fluor is a registered trademark of Air Products & Chemicals, Inc.

Safety & Documentation

Safety Information

Signal word 
Danger
Precautionary statements 
Supplemental Hazard Statements 
Contact with water liberates toxic gas., Reacts violently with water.
RIDADR 
UN 3286 8(6.1)(3) / PGII
WGK Germany 
3
Flash Point(F) 
<50 °F
Flash Point(C) 
<10 °C
Protocols & Articles

Articles

Reagents for Fluorination

The trifluoromethyl substituent has long been recognized for the positive influence it can have on the biological activity of molecules. Professor William Dolbier, Jr. (University of Florida) has dev...
Aldrich ChemFiles 2007, 7.1, 11.

Peer-Reviewed Papers
15

References

Related Products

related product

Product #

Description

Add to Cart

08168 Timestrip Plus 8 °C

Technical Service:

Our team of scientists has experience in all areas of research including Life Science, Material Science, Chemical Synthesis, Chromatography, Analytical and many others.

Bulk Ordering & Pricing:

Need larger quantities for your development, manufacturing or research applications?