EMAIL THIS PAGE TO A FRIEND
E33505 Sigma-Aldrich

Ethyl isonipecotate

98%

Synonym: Ethyl 4-piperidinecarboxylate, Piperidin-4-carboxylic acid ethyl ester

  • CAS Number 1126-09-6

  • Empirical Formula (Hill Notation) C8H15NO2

  • Molecular Weight 157.21

  •  Beilstein/REAXYS Number 118419

  •  EC Number 214-416-7

  •  MDL number MFCD00006003

  •  PubChem Substance ID 24894508

  •  NACRES NA.22

Purchase

Properties

Related Categories Building Blocks, C8, Chemical Synthesis, Heterocyclic Building Blocks, Piperidines More...
InChI Key   RUJPPJYDHHAEEK-UHFFFAOYSA-N
assay   98%
refractive index   n20/D 1.459 (lit.)
bp   204 °C (lit.)
density   1.02 g/mL at 25 °C (lit.)

Description

Application

Reactant for synthesis of:
• SMN protein modulators
• β-aryl and β-amino-substituted aliphatic esters by rhodium catalyzed tandem double bond migration/conjugate addition
• Nitroethylenediamines by nucleophilic ring opening of nitroimidazolidinone
• RhoA inhibitors for cardiovascular disease therapy
• Saccharin derived Mannich bases as antimicrobials and antioxidants

Reactant for one-pot reductive amination and Suzuki-Miyaura cross coupling of formyl aryl and heteroaryl MIDA boronates

Packaging

25, 100 g in glass bottle

Safety & Documentation

Safety Information

RIDADR 
NONH for all modes of transport
WGK Germany 
3
Flash Point(F) 
176 °F
Flash Point(C) 
80 °C

Meet Synthia - Retrosynthesis Sofware
Protocols & Articles
Related Products

Technical Service:

Our team of scientists has experience in all areas of research including Life Science, Material Science, Chemical Synthesis, Chromatography, Analytical and many others.

Bulk Ordering & Pricing:

Need larger quantities for your development, manufacturing or research applications?