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H1384 Sigma-Aldrich

Hypotaurine

≥98% (TLC)

Synonym: 2-Aminoethanesulfinic acid

  • CAS Number 300-84-5

  • Empirical Formula (Hill Notation) C2H7NO2S

  • Molecular Weight 109.15

  •  MDL number MFCD00038197

  •  PubChem Substance ID 57654233

  •  NACRES NA.22

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Properties

Related Categories Amino Acid, Building Blocks, Cell Biology, Cell Signaling and Neuroscience, Chemical Synthesis,
Quality Level   200
assay   ≥98% (TLC)
color   white to off-white
solubility   H2O: 100 mg/mL
SMILES string   NCCS(O)=O
InChI   1S/C2H7NO2S/c3-1-2-6(4)5/h1-3H2,(H,4,5)
InChI key   VVIUBCNYACGLLV-UHFFFAOYSA-N

Description

Application

Hypotaurine has been used as a supplement in fertilization medium (Fert- tyrode albumin lactate pyruvate (TALP)), which used in in-vitro fertilization and evaluation of embryo development. It is also used as a H2S scavenger.

Packaging

1 g in poly bottle

100, 250 mg in poly bottle

10 mg in glass bottle

Biochem/physiol Actions

Hypotaurine, a cystamine analog, is the precursor for taurine synthesis. It can act as an antioxidant and singlet oxygen scavenger, thereby protecting cells from oxidative damage. Hypotaurine is reported to play an important role in the maintenance and stimulation of sperm motility and also in vitro fertilization and embryo development.

Antioxidant that binds hydroxyl radicals. Endogenous inhibitory neuromodulator that is blocked by strychnine and picrotoxin. Inhibits the Na2+-dependent transport of GABA and β-alanine. It is a degradation product of cysteine and a precursor of taurine.

Other Notes

Tandem Mass Spectrometry data independently generated by Scripps Center for Metabolomics is available to view or download in PDF. H1384.pdf Tested metabolites are featured on Scripps Center for Metabolomics METLIN Metabolite Database. To learn more, visit sigma.com/metlin.

Safety & Documentation

Safety Information

Symbol 
GHS07  GHS07
Signal word 
Warning
Hazard statements 
Precautionary statements 
Personal Protective Equipment 
RIDADR 
NONH for all modes of transport
WGK Germany 
3

Documents

Certificate of Analysis (COA)

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Certificate of Origin (COO)

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Meet Synthia - Retrosynthesis Sofware
Protocols & Articles

Articles

MSMLS Online Plate Map

Metabolite descriptors included with the software download upon purchase of the product include: Name, Parent CID, molecular formula, molecular weight, CAS, ChEBI, HMDB ID, PubChem Compound and Subst...
Keywords: Mass spectrometry, Metabolites

Peer-Reviewed Papers
15

References

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