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H43806 Sigma-Aldrich

4-Hydroxy-2-methylquinoline

98.5%

Synonym: 2-Methyl-4-quinolinol

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Properties

Related Categories Building Blocks, C8 to C10, Chemical Synthesis, Heterocyclic Building Blocks, Quinolines More...
assay   98.5%
SMILES string   Cc1cc(O)c2ccccc2n1
InChI   1S/C10H9NO/c1-7-6-10(12)8-4-2-3-5-9(8)11-7/h2-6H,1H3,(H,11,12)
InChI key   NWINIEGDLHHNLH-UHFFFAOYSA-N

Description

Application

4-Hydroxy-2-methylquinoline can be used as an intermediate in the synthesis of a wide range of medicinally important compounds such as:
• Synthesis of 2-(quinolin-4-yloxy)acetamides as potent antitubercular agents.
• Synthesis of 2-arylethenylquinoline derivatives for the treatment of Alzheimer′s disease.
• Synthesis of 1,10-diethoxy-1H-pyrano[4,3-b]quinolones as antibacterial agents.
• Synthesis of phenylimidazole-pyrazolo[1,5-c]quinazolines as potent phophodiesterase 10A (PDE10A) inhibitors.

Packaging

10, 50 g in poly bottle

Safety & Documentation

Safety Information

Symbol 
GHS07  GHS07
Signal word 
Warning
Hazard statements 
Precautionary statements 
Personal Protective Equipment 
RIDADR 
NONH for all modes of transport
WGK Germany 
3

Meet Synthia - Retrosynthesis Sofware
Protocols & Articles
Peer-Reviewed Papers
15

References

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