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QBD10318 Sigma-Aldrich

m-dPEG®24-amine

  • Empirical Formula (Hill Notation) C49H101NO24

  • Molecular Weight 1088.32

  •  MDL number MFCD11041163

  •  PubChem Substance ID 329823916

  •  NACRES NA.22

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Properties

Related Categories Chemical Biology, Chemical Synthesis, Monofunctional, PEGylation, dPEGs from Quanta Biodesign More...
assay   >90%
form   solid or viscous liquid
reaction suitability   reagent type: chemical modification reagent
reactivity: carboxyl reactive
  reagent type: cross-linking reagent
polymer architecture   shape : linear
functionality : monofunctional
shipped in   ambient
storage temp.   −20°C
SMILES string   NCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOC

Description

Features and Benefits

The m-dPEG®24-amine provides a variety of means to modify small molecules, peptides, proteins, and functionalized surfaces (metals, glass, and others). This single molecular weight methoxy-terminated dPEG® molecule is hydrophilic and non-immunogenic with a spacer of exact length (86.1 Å). Modification with m-dPEG® reagent can improve water solubility, increase hydrodynamic volume, eliminate or reduce non-specific binding, protect peptides and proteins from proteolysis, reduce or eliminate immunogenicity, and increase serum half-life in vivo. The m-dPEG®24-amine products react with carboxylic acids and active esters.

Legal Information

Products Protected under U.S. Patents # 7,888,536 B2

dPEG is a registered trademark of Quanta BioDesign

Safety & Documentation

Safety Information

RIDADR 
NONH for all modes of transport
Flash Point(F) 
Not applicable
Flash Point(C) 
Not applicable

Documents

Certificate of Analysis (COA)

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Protocols & Articles

Articles

Polyethylene Glycol (PEG) Selection Guide

Poly(ethylene glycol) (PEG) is a synthetic, hydrophilic, biocompatible polymer with widespread use in biomedical and other applications. PEGs are synthesized using a ring-opening polymerization of et...
Keywords: Adhesion, Bacterial conjugations, Click chemistry, Molecular biology, PEGylations, Polymerization reactions, Ring-opening polymerization

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