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S3836 Aldrich

Spermine

98%

Synonym: N,N′-Bis(3-aminopropyl)-1,4-diaminobutane, Gerontine, Musculamine, Neuridine

  • CAS Number 71-44-3

  • Linear Formula NH2(CH2)3NH(CH2)4NH(CH2)3NH2

  • Molecular Weight 202.34

  •  Beilstein Registry Number 1750791

  •  EC Number 200-754-2

  •  MDL number MFCD00008215

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Properties

InChI Key   PFNFFQXMRSDOHW-UHFFFAOYSA-N
assay   98%
bp   150 °C/5 mmHg(lit.)
mp   28-30(lit.)

Description

Biochem/physiol Actions

Mixed NMDA glutamate receptor agonist/antagonist at the polyamine site. Neuroprotective effects have been observed at high concentrations (1 mM), while neurotoxicity is observed at lower concentrations. It enhances agonist effectiveness at the strychnine-insensitive glycine site. Plays a role in cellular proliferation and differentiation; inhibits neuronal nitric oxide synthase (nNOS).

Safety & Documentation

Safety Information

RIDADR 
UN 3259 8/PG 2
WGK Germany 
3
RTECS 
EJ7175000
Flash Point(F) 
230 °F
Flash Point(C) 
110 °C
Protocols & Articles
Peer-Reviewed Papers
15

References

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Description

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S3256 Spermine, ≥97%

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