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T35009 Sigma-Aldrich

L-Thyroxine sodium salt pentahydrate

99%

Synonym: 3-[4-(4-Hydroxy-3,5-diiodophenoxy)-3,5-diiodophenyl]-L-alanine sodium salt, Sodium levothyroxine, T4

  • CAS Number 6106-07-6

  • Linear Formula HOC6H2I2OC6H2I2CH2CH(NH2)COONa · 5H2O

  • Molecular Weight 888.93

  •  Beilstein/REAXYS Number 5721845

  •  EC Number 200-221-4

  •  MDL number MFCD00149110

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Properties

InChI Key   JMHCCAYJTTWMCX-QWPJCUCISA-M
assay   99%
optical activity   [α]20/D −6.6°, c = 3 in 1 M NaOH, C2H5OH, 1:2
mp   207-210 (dec.) (lit.)

Description

Biochem/physiol Actions

L-Thyroxine (T4) and triiodo-L-thyronine (T3) are iodine-containing hormones produced from thyroglobulin in the thyroid follicular cells. The stimulation of metabolic rate and regulation of growth and development by these hormones appear to be due to their effects on DNA transcription and thus, protein synthesis.

Safety & Documentation

Safety Information

RIDADR 
NONH for all modes of transport
WGK Germany 
3
RTECS 
YP2833760
Protocols & Articles
Peer-Reviewed Papers
15

References

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T2501 L-Thyroxine sodium salt pentahydrate, ≥98% (HPLC), powder

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