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A4926 Sigma-Aldrich

1,2-Bis(2-Aminophenoxy)ethane-N,N,N′,N′-tetraacetic acid

98%

Synonym: 2,2′-(Ethylenedioxy)dianiline-N,N,N′,N′-tetraacetic acid, BAPTA, Ethylenedioxybis(o-phenylenenitrilo)tetraacetic acid

  • CAS Number 85233-19-8

  • Empirical Formula (Hill Notation) C22H24N2O10

  • Molecular Weight 476.43

  •  Beilstein/REAXYS Number 5192406

  •  MDL number MFCD00036255

  •  PubChem Substance ID 57653856

  •  NACRES NA.23

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Properties

Related Categories Biochemicals and Reagents, Calcium Indicators, Calcium Signaling Research Tools, Cell Biology, Cell Signaling and Neuroscience,
Quality Level   200
assay   98%
storage temp.   2-8°C
SMILES string   OC(=O)CN(CC(O)=O)c1ccccc1OCCOc2ccccc2N(CC(O)=O)CC(O)=O
InChI   1S/C22H24N2O10/c25-19(26)11-23(12-20(27)28)15-5-1-3-7-17(15)33-9-10-34-18-8-4-2-6-16(18)24(13-21(29)30)14-22(31)32/h1-8H,9-14H2,(H,25,26)(H,27,28)(H,29,30)(H,31,32)
InChI key   FTEDXVNDVHYDQW-UHFFFAOYSA-N

Description

General description

In nature 1,2-Bis(2-Aminophenoxy)ethane-N,N,N′,N′-tetra acetic acid (BAPTA) is a main metabolic product of BAPTA -AM (BAPTA-tetra(actoxymethyl ester), a neuro protective agent in cerebral ischemia, in rats.BAPTA is an intercellular Ca2+ chelator.

Application

Used to study morphological and signaling events of Ca2+ deficiency.

Packaging

1, 5 g in poly bottle

250 mg in poly bottle

Safety & Documentation

Safety Information

Personal Protective Equipment 
RIDADR 
NONH for all modes of transport
WGK Germany 
WGK 3
Flash Point(F) 
Not applicable
Flash Point(C) 
Not applicable

Documents

Certificate of Analysis (COA)

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Certificate of Origin (COO)

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Protocols & Articles

Articles

Sensor Dyes

In 1998 R.F. Furchgott, L.J. Ignarro, and F. Murad received the Nobel Prize in Physiology and Medicine for their discoveries concerning nitric oxide as a signaling molecule in the cardiovascular syst...
Monika Baeumle
BioFiles 2011, 6.3, 23.
Keywords: Applications, Biochemistry, Biological processes, Cancer, Cardiovascular, Central Nervous System, Diseases, Extinction coefficient, Indicators, Inflammation, Methods, Microscopy, Neurotransmission, Sol-gel, Type

Peer-Reviewed Papers
15

References

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