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A76001 Sigma-Aldrich

(±)-3-Amino-1,2-propanediol

97%

  • CAS Number 616-30-8

  • Linear Formula NH2CH2CH(OH)CH2OH

  • Molecular Weight 91.11

  •  Beilstein/REAXYS Number 1719121

  •  EC Number 210-475-8

  •  MDL number MFCD00008140

  •  PubChem Substance ID 24891256

  •  NACRES NA.22

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Properties

Related Categories Amino Alcohols, Building Blocks, Chemical Synthesis, Organic Building Blocks, Oxygen Compounds More...
Quality Level   200
assay   97%
refractive index   n20/D 1.492 (lit.)
bp   264-265 °C/739 mmHg (lit.)
density   1.175 g/mL at 25 °C (lit.)
SMILES string   NCC(O)CO
InChI   1S/C3H9NO2/c4-1-3(6)2-5/h3,5-6H,1-2,4H2
InChI key   KQIGMPWTAHJUMN-UHFFFAOYSA-N

Description

Application

(±)-3-Amino-1,2-propanediol is used as a reactant in the synthesis of lipid-like delivery molecules(lipidoids) for RNA interference (RNAi) therapeutics. It is also used in the synthesis of the bioactive template to prepare cationic α-helical polypeptides and various cationic polymers for gene delivery.

Packaging

5, 25, 100 g in glass bottle

Safety & Documentation

Safety Information

Symbol 
GHS05  GHS05
Signal word 
Danger
Hazard statements 
Precautionary statements 
RIDADR 
UN 2735PSN1 8 / PGII
WGK Germany 
WGK 2
RTECS 
TY2800000
Flash Point(F) 
235.4 °F - closed cup
Flash Point(C) 
113 °C - closed cup

Documents

Certificate of Analysis (COA)

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Certificate of Origin (COO)

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Meet Synthia - Retrosynthesis Sofware
Protocols & Articles
Peer-Reviewed Papers
15

References

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