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B62404 Sigma-Aldrich

1-Bromo-3-chloropropane

99%

Synonym: I-BCP, Trimethylene bromochloride, Trimethylene chlorobromide

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Properties

Related Categories Alkyl, Building Blocks, Chemical Synthesis, Halogenated Hydrocarbons, Organic Building Blocks More...
InChI Key   MFESCIUQSIBMSM-UHFFFAOYSA-N
assay   99%
refractive index   n20/D 1.486 (lit.)
bp   144-145 °C(lit.)
density   1.592 g/mL at 25 °C (lit.)

Description

Application

1-Bromo-3-chloropropane is generally used as C3 linker/spacer in a wide range of molecules including medicinally important compounds. Some of the examples are:
• Synthesis of polymer nanoparticles (NPs) to deliver doxorubicin, camptothecin, and cisplatin.
• Synthesis of antiprion active acridine derivatives for prion infection.
• Total synthesis of aspidospermine, aspidospermidine, and quebrachamine and (±)-crispine A.

Packaging

1 kg in glass bottle

250 g in glass bottle

Safety & Documentation

Safety Information

Symbol 
GHS06  GHS06
Signal word 
Danger
Hazard statements 
RIDADR 
UN 2688 6.1 / PGIII
WGK Germany 
3
RTECS 
TX4113000
Flash Point(F) 
>284 °F
Flash Point(C) 
>140 °C

Documents

Certificate of Analysis

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Certificate of Origin

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Meet Synthia - Retrosynthesis Sofware
Protocols & Articles
Peer-Reviewed Papers
15

References

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