JKA0001 Sigma-Aldrich


average Mn 40,000

Synonym: Y-PEG-NHS

  • Linear Formula ((CH3O(CH2CH2O)nCH2CH2)(CH3(CH2CH2O)nCH2CO)NCH2COOC4H4O2N

  •  NACRES NA.23



Related Categories Materials Science, Multi-arm PEGs, PEG Dendrimers and Multi-arm PEGs, Poly(ethylene glycol) and Poly(ethylene oxide), Polymer Science,
mol wt   average Mn 40,000
polymer architecture   shape : Y-shape
functionality : monofunctional
reaction suitability  
reactivity: amine reactive


General description

Y-shape PEG NHS from JenKem Technology is a Succinimidyl Carboxymethyl Ester with two PEG arms, reactive towards the amino group of lysine(s) on proteins or other biologics. Amine PEGylation with Y-shape PEG NHS can be completed in less than 1hr at pH 7-8. JenKem proprietary Y-shape PEGs are more selective, due to their sterically bulky structure.


Applications may include: bioconjugation, drug delivery, PEG hydrogel, crosslinker, and surface functionalization

Legal Information

Product of JenKem Technology

Safety & Documentation

Safety Information

NONH for all modes of transport
WGK Germany 
Flash Point(F) 
Not applicable
Flash Point(C) 
Not applicable
Protocols & Articles


Applications of Y-Shape Peg Derivatives for Drug Delivery

The immune system protects the body from disease by resisting the invasion of foreign molecules into its cells, for example peptides and proteins are hydrolyzed by proteolytic enzymes; nucleic acids ...
Dr. Hui Zhu
Material Matters, 2016, 11.3
Keywords: Antibiotics, Antitumor agents, Antivirals, Bacterial conjugations, Cancer, Clinical, Degradations, Digestions, Eliminations, Enzyme activity, Genetic, Hormones, Indicators, Ion-exchange chromatography, Metabolism, Oxidations, PEGylations, Pharmaceutical, Phosphorylations, Reductions, Reproduction

Polyethylene Glycol (PEG) Selection Guide

Poly(ethylene glycol) (PEG) is a synthetic, hydrophilic, biocompatible polymer with widespread use in biomedical and other applications. PEGs are synthesized using a ring-opening polymerization of et...
Keywords: Adhesion, Bacterial conjugations, Click chemistry, Molecular biology, PEGylations, Polymerization reactions, Ring-opening polymerization

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