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M1021 Aldrich

1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine

Synonym: MPTP

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Properties

InChI Key   PLRACCBDVIHHLZ-UHFFFAOYSA-N
drug control   regulated under CDSA - not available from Sigma-Aldrich Canada
bp   128-132 °C/12 mmHg(lit.)

Description

Biochem/physiol Actions

Dopaminergic neurotoxin.

Warning

Reportedly causes a severe and irreversible Parkinsonism condition in humans and monkeys. New Engl. J. Med. 1983, 309, 310. Science 1983, 219, 979. ibid. 1984, 224, 1083, 1451. ibid. 1984, 225, 529. J. Med. Chem. 1985, 28, 997.

Safety & Documentation

Safety Information

Symbol 
Signal word 
Danger
Hazard statements 
Precautionary statements 
RIDADR 
UN 2811 6.1 / PGII
WGK Germany 
3
RTECS 
UT8358900
Flash Point(F) 
235.4 °F
Flash Point(C) 
113 °C
Protocols & Articles
Peer-Reviewed Papers
15

References

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