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M18655 Sigma-Aldrich

4-Methoxyphenol

ReagentPlus®, 99%

Synonym: 4-Hydroxyanisole, 4-MP, p-Methoxyphenol, HQMME, Hydroquinone monomethyl ether, MEHQ, MQ-F, p-Guaiacol

  • CAS Number 150-76-5

  • Linear Formula CH3OC6H4OH

  • Molecular Weight 124.14

  •  Beilstein/REAXYS Number 507924

  •  EC Number 205-769-8

  •  MDL number MFCD00002332

  •  PubChem Substance ID 24896699

  •  NACRES NA.22

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Properties

Related Categories Building Blocks, C6 to C8, Chemical Synthesis, Organic Building Blocks, Oxygen Compounds,
grade   ReagentPlus®
vapor density   4.3 (vs air)
vapor pressure   <0.01 mmHg ( 20 °C)
InChI Key   NWVVVBRKAWDGAB-UHFFFAOYSA-N
assay   99%
autoignition temp.   789 °F
bp   243 °C (lit.)
mp   55-57 °C (lit.)

Description

Application

4-methoxyphenol may be used in the synthesis of butylated hydroxy anisoles via alkylation with methyl tert-butyl ether over a non-zeolitic solid acidic catalyst. This process is eco-friendly when compared to the Friedel-Crafts alkylation reaction. 4-MP may also react with aqueous nitrous acid to form 2-nitro-4-methoxyphenol and benzoquinone in varying ratios depending on the reaction conditions. 4-MP can be used as a building block in designing β-cyclodextrin 4-methoxyphenol conjugates that can be potential ligands for drug complexation.

Packaging

1 kg in poly bottle

100, 500 g in poly bottle

50 lb in fiber drum

5 g in glass bottle

Legal Information

ReagentPlus is a registered trademark of Sigma-Aldrich Co. LLC

Safety & Documentation

Safety Information

Symbol 
Signal word 
Warning
Hazard statements 
Personal Protective Equipment 
RIDADR 
NONH for all modes of transport
WGK Germany 
1
RTECS 
SL7700000
Flash Point(F) 
269.6 °F
Flash Point(C) 
132 °C

Documents

Certificate of Analysis (COA)

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Certificate of Origin (COO)

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Protocols & Articles

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Peer-Reviewed Papers
15

References

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